Surface adhesins of Staphylococcus aureus

SR Clarke, SJ Foster - Advances in microbial physiology, 2006 - Elsevier
An important facet in the interaction between Staphylococcus aureus and its host is the
ability of the bacterium to adhere to human extracellular matrix components and serum …

[HTML][HTML] Mammalian epidermis: a compendium of lipid functionality

M Vietri Rudan, FM Watt - Frontiers in physiology, 2022 - frontiersin.org
Mammalian epidermis is a striking example of the role of lipids in tissue biology. In this
stratified epithelium, highly specialized structures are formed that leverage the hydrophobic …

Effects of axotomy and intraocular administration of NT-4, NT-3, and brain-derived neurotrophic factor on the survival of adult rat retinal ganglion cells. A quantitative in …

P Peinado-Ramon, M Salvador… - … & visual science, 1996 - iovs.arvojournals.org
PURPOSE: To investigate in vivo the survival of retinal ganglion cells (RGC) 4 to 14 days
after optic nerve (ON) transection alone or in combination wih a single intraocular injection …

[HTML][HTML] Antigen specificity enhances disease control by Tregs in vitiligo

Z Mukhatayev, ER Dellacecca, C Cosgrove… - Frontiers in …, 2020 - frontiersin.org
Vitiligo is an autoimmune skin disease characterized by melanocyte destruction. Regulatory
T cells (Tregs) are greatly reduced in vitiligo skin, and replenishing peripheral skin Tregs …

Ceramide signaling in mammalian epidermis

Y Uchida - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2014 - Elsevier
Ceramide, the backbone structure of all sphingolipids, as well as a minor component of
cellular membranes, has a unique role in the skin, by forming the epidermal permeability …

[HTML][HTML] Abnormalities of sphingolipids metabolic pathways in the pathogenesis of psoriasis

B Burger, RN Sagiorato, I Cavenaghi, HG Rodrigues - Metabolites, 2023 - mdpi.com
Psoriasis is immune-mediated skin disorder affecting thousands of people. Sphingolipids
(SLs) are bioactive molecules present in the epidermis, involved in the following cellular …

Suppression of epidermal growth factor receptor signaling by protein kinase C-α activation requires CD82, caveolin-1, and ganglioside

X Wang, Q Yan, P Sun, JW Liu, L Go, SM McDaniel… - Cancer research, 2007 - AACR
Activation of protein kinase C (PKC)-α decreases normal and neoplastic cell proliferation by
inhibiting epidermal growth factor receptor (EGFR)-related signaling. The molecular …

Sphingolipids as receptor modulators: an overview

AJ Yates, A Rampersaud - Annals of the New York Academy of …, 1998 - Wiley Online Library
Glycosphingolipids are amphipathic compounds that exist mainly in the plasmalemma with
their oligosaccharide portion protruding into the extracellular environment. In this position …

Inhibition of human neuroblastoma cell proliferation and EGF receptor phosphorylation by gangliosides GM1, GM3, GD1A and GT1B

BL Mirkin, SH Clark, C Zhang - Cell Proliferation, 2002 - Wiley Online Library
The inhibitory action of gangliosides GT1B, GD1A, GM3 and GM1 on cell proliferation and
epidermal growth factor receptor (EGFR) phosphorylation was determined in the N‐myc …

[HTML][HTML] Ganglioside GM3 blocks the activation of epidermal growth factor receptor induced by integrin at specific tyrosine sites

XQ Wang, P Sun, AS Paller - Journal of Biological Chemistry, 2003 - ASBMB
The epidermal growth factor receptor (EGFR) can be activated by both direct ligand binding
and cross-talk with other molecules, such as integrins. This integrin-mediated cross-talk with …