Dietary PUFA and cancer

S Abel, S Riedel, WCA Gelderblom - Proceedings of the Nutrition …, 2014 - cambridge.org
The aim of the present paper is to give a brief overview on the role of dietary fat in
carcinogenesis and as possible anticancer agents. Dietary fat is an essential nutrient and …

Low-density lipoprotein docosahexaenoic acid nanoparticles induce ferroptotic cell death in hepatocellular carcinoma

W Ou, RS Mulik, A Anwar, JG McDonald, X He… - Free Radical Biology …, 2017 - Elsevier
Low-density lipoprotein nanoparticles reconstituted with the natural omega-3 fatty acid,
docosahexaenoic acid (LDL-DHA), have been reported to selectively kill hepatoma cells …

Omega-3 fatty acids in prevention of diabetic retinopathy

T Behl, A Kotwani - Journal of Pharmacy and Pharmacology, 2017 - academic.oup.com
Objectives To review the competence of Omega-3 fatty acids in restricting the progression,
thereby leading to prevention of diabetic retinopathy. Key findings Owing to their anti …

Docosahexaenoic Acid (DHA) Provides Neuroprotection in Traumatic Brain Injury Models via Activating Nrf2-ARE Signaling

W Zhu, Y Ding, W Kong, T Li, H Chen - Inflammation, 2018 - Springer
In this study, we explored the neuroprotective effects of docosahexaenoic acid (DHA) in
traumatic brain injury (TBI) models. In this study, we first confirmed that DHA was …

Polyunsaturated fatty acids induce ovarian cancer cell death through ROS-dependent MAP kinase activation

A Tanaka, A Yamamoto, K Murota, T Tsujiuchi… - Biochemical and …, 2017 - Elsevier
Free fatty acids not only play a role in cell membrane construction and energy production but
also exert diverse cellular effects through receptor and non-receptor mechanisms. Moreover …

[HTML][HTML] Raman Imaging—A Valuable Tool for Tracking Fatty Acid Metabolism—Normal and Cancer Human Colon Single-Cell Study

K Beton-Mysur, M Kopec, B Brozek-Pluska - International Journal of …, 2024 - mdpi.com
Altered metabolism of lipids is a key factor in many diseases including cancer. Therefore,
investigations into the impact of unsaturated and saturated fatty acids (FAs) on human body …

[HTML][HTML] Epitelial-to-mesenchimal transition and invasion are upmodulated by tumor-expressed granzyme B and inhibited by docosahexaenoic acid in human …

D D'Eliseo, G Di Rocco, R Loria, S Soddu… - Journal of experimental …, 2016 - Springer
Abstract Background Granzyme B (GrB) is a serine protease, traditionally known as
expressed by cytotoxic lymphocytes to induce target cell apoptosis. However, it is emerging …

[HTML][HTML] The Modulatory Effects of Fatty Acids on Cancer Progression

AJF Westheim, LM Stoffels, LJ Dubois… - Biomedicines, 2023 - mdpi.com
Cancer is the second leading cause of death worldwide and the global cancer burden rises
rapidly. The risk factors for cancer development can often be attributed to lifestyle factors, of …

[HTML][HTML] Omega-3 polyunsaturated Fatty acids as potential chemopreventive agent for gastrointestinal cancer

JM Park, SH Kwon, YM Han, KB Hahm… - Journal of cancer …, 2013 - ncbi.nlm.nih.gov
Omega-3 polyunsaturated fatty acids (n-3 PUFAs), particularly eicosapentanoic acid (EPA)
and docosahexanoic acid (DHA), has been acknowledged as essential very long-chain fatty …

[HTML][HTML] Associations of long chain polyunsaturated fatty acids with bone mineral density and bone turnover in postmenopausal women

O Feehan, PJ Magee, LK Pourshahidi… - European Journal of …, 2023 - Springer
Purpose The immunomodulatory properties of n-3 long chain polyunsaturated fatty acids
(LCPUFA) are reported to reduce bone loss through alteration of bone remodelling and n-3 …