In response to environmental cues, enzymes that influence the functions of proteins, through
reversible post-translational modifications supervise the coordination of cell behavior like …

The identification of the mutation causing Huntington's disease (HD) has led to the
generation of a large number of mouse models. These models are used to further enhance …

Huntington's disease (HD) is an autosomal dominant inherited neurodegenerative disorder
that is caused by a CAG expansion in the Huntingtin (HTT) gene, leading to HTT inclusion …

Denervation can activate the catabolic pathway in skeletal muscle and lead to progressive
skeletal muscle atrophy. At present, there is no effective treatment for muscle atrophy …

Promoter‐associated long non‐coding RNA s (lnc RNA s) regulate the expression of
adjacent genes; however, precise roles of these lnc RNA s in skeletal muscle remain largely …

Huntington's disease is caused by the expansion of a CAG repeat within exon 1 of the HTT
gene, which is unstable, leading to further expansion, the extent of which is brain region and …

Skeletal muscle mass is regulated by the coordinated activation of several anabolic and
catabolic pathways. The endoplasmic reticulum (ER) is a major site of protein folding and a …

Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by
pathogenic expansions of the triplet cytosine-adenosine-guanosine (CAG) within the …

Huntington's disease (HD) is a progressive neurodegenerative disorder caused by an
expanded CAG repeat within the huntingtin (HTT) gene. The Q140 and HdhQ150 knock‐in …

Abstract Background Although Huntington's disease (HD) is usually thought of as a triad of
motor, cognitive, and psychiatric symptoms, there is growing appreciation of HD as a …