Progress in deciphering the genetic architecture of human sensorineural hearing
impairment (SNHI) or loss, and multidisciplinary studies of mouse models, have led to the …

Hearing loss is a severe high unmet need condition affecting more than 1.5 billion people
globally. There are no licensed medicines for the prevention, treatment or restoration of …

Although sudden sensorineural hearing loss (SSNHL) is a serious condition, there are
currently no approved drugs for its treatment. Nevertheless, there is a growing …

Hair cell death induced by excessive reactive oxygen species (ROS) has been identified as
the major pathogenesis of noise‐induced hearing loss (NIHL). Recent studies have …

Fatty acid-binding protein 7 (FABP7) is vital for uptake and trafficking of fatty acids in the
nervous system. To investigate the involvement of FABP7 in noise-induced hearing loss …

Exposure to combinations of environmental toxins is growing in prevalence; and therefore,
understanding their interactions is of increasing societal importance. Here, we examined the …

Noise‐induced hearing loss (NIHL), a prevalent sensory disability affecting a majority of the
global population, is dominantly induced by mitochondrial dysfunction and oxidative stress …

Tinnitus is a well-known pathological entity in clinical practice. However, the
pathophysiological mechanisms behind tinnitus seem to be elusive and cannot provide a …

GABA B receptors are G-protein coupled receptors for the inhibitory neurotransmitter GABA.
Functional GABA B receptors are formed as heteromers of GABA B1 and GABA B2 subunits …

Over-production of reactive oxygen species (ROS) in the inner ear can be triggered by a
variety of pathological events identified in animal models after traumatic noise exposure. Our …