Trametinib, a MEK1/2 Inhibitor, Protects Mice from Cisplatin-and Noise-Induced Hearing Loss

RD Lutze, MA Ingersoll, RG Kelmann, T Teitz - Pharmaceuticals, 2024 - mdpi.com
Hearing loss is one of the most common types of disability; however, there is only one FDA-
approved drug to prevent any type of hearing loss. Treatment with the highly effective …

An Active Indoor Noise Control System Based on CS Algorithm

W Tao, Y Ma, S Xiao, Q Cheng, Y Wang, Z Chen - Applied Sciences, 2022 - mdpi.com
Environmental noise causes enormous harm to human health. This research suggests an
active noise control (ANC) system based on the cuckoo search (CS) algorithm to reduce …

[HTML][HTML] Changes of FGF23 and hearing in chronic renal failure and their correlation analysis

J Li, J Nie, Z Zhou, M Guo, Q Yang, D Yuan, J Huang… - Cytokine, 2024 - Elsevier
Background To explore the association between fibroblast growth factor 23 (FGF23) and
hearing in chronic renal failure (CRF). Methods Pure tone audiometry was used to detect the …

[HTML][HTML] Considering the protective effect of exendin-4 against oxidative stress in spiral ganglion neurons

H Wu, Y Ou, S Wang, F Yu, X Fan… - Iranian Journal of …, 2023 - ncbi.nlm.nih.gov
Objective (s): The protection of spiral ganglion neurons (SGNs) is crucial for hearing loss.
Exendin-4 has been shown to have neuroprotective effects in several neurological …

[PDF][PDF] A mechanistic study of tinnitus and hyperacusis in relation to temporary conductive hearing loss

R Jeche, MR Maslin, M Park - Unpublished manuscript]. School …, 2023 - ir.canterbury.ac.nz
Previous research has shown that unilateral auditory deprivation can induce physiological
and perceptual changes in the auditory system of normal hearing adults (Brotherton et al …

Isolation and Culture of Primary Cochlear Hair Cells from Neonatal Mice

KY Wu, BT Wang, YJ He, JY Xie, ZC Chen… - JoVE (Journal of …, 2023 - jove.com
Cochlear hair cells are the sensory receptors of the auditory system. These cells are located
in the organ of Corti, the sensory organ responsible for hearing, within the osseous labyrinth …

Hydrogen Gas Inhalation Attenuates Acute Impulse Noise Trauma: A Preclinical In Vivo Study

P Videhult Pierre, A Fransson… - Annals of Otology …, 2023 - journals.sagepub.com
Objective: Molecular hydrogen (H2) has shown therapeutic potential in several oxidative
stress-related conditions in humans, is well-tolerated, and is easily administered via …

Author Spotlight: Advancements in Cultivating Mouse Hair Cells for Auditory Research

KY Wu, BT Wang, YJ He, JY Xie, ZC Chen… - JoVE (Journal of …, 2023 - jove.com
Cochlear hair cells are the sensory receptors of the auditory system. These cells are located
in the organ of Corti, the sensory organ responsible for hearing, within the osseous labyrinth …

FDA-Approved MEK1/2 Inhibitor, Trametinib, Protects Mice from Cisplatin and Noise-Induced Hearing Loss

RD Lutze, MA Ingersoll, RG Kelmann, T Teitz - bioRxiv, 2024 - biorxiv.org
Hearing loss is one of the most common types of disability; however, there is only one FDA-
approved drug to prevent any type of hearing loss. Treatment with the highly effective …

[HTML][HTML] 声学治疗噪声性听力损失的耳鸣

陈默, 杨见明 - Advances in Clinical Medicine, 2023 - hanspub.org
目的: 噪声性听力损失(NIHL) 是一段时间过度暴露于噪声引起的感音神经性耳聋. 耳鸣是NIHL
最常见的症状之一, 它会给患者造成痛苦, 并对他们的生活质量产生不利影响. 近年来 …