Calcium is an essential second messenger in endothelial cells and plays a pivotal role in
regulating a number of physiologic processes, including cell migration, angiogenesis …

The microvascular endothelial cell monolayer localized at the critical interface between the
blood and vessel wall has the vital functions of regulating tissue fluid balance and supplying …

The endothelial monolayer partitioning underlying tissue from blood components in the
vessel wall maintains tissue fluid balance and host defense through dynamically opening …

The blood-brain barrier (BBB) is formed by the endothelial cells of cerebral microvessels,
providing a dynamic interface between the peripheral circulation and the central nervous …

Vascular endothelial growth factors (VEGFs) are key regulators of permeability. The
principal evidence behind how they increase vascular permeability in vivo and in vitro and …

Low-molecular-weight vascular-disrupting agents (VDAs) cause a pronounced shutdown in
blood flow to solid tumours, resulting in extensive tumour-cell necrosis, while they leave the …

The endothelium is a semi‐permeable barrier that regulates the flux of liquid and solutes,
including plasma proteins, between the blood and surrounding tissue. The permeability of …

The transient receptor potential (TRP) superfamily consists of a large number of
nonselective cation channels with variable degree of Ca2+-permeability. The 28 mammalian …

Air pollution is the most important environmental risk factor for disease and premature death,
and exposure to combustion particles from vehicles is a major contributor. Human …

Vascular smooth muscle (VSM) cells, endothelial cells (EC), and pericytes that form the
walls of vessels in the microcirculation express a diverse array of ion channels that play an …