Mesenchymal stem cell-derived extracellular vesicles for immunomodulation and regeneration: a next generation therapeutic tool?
M Kou, L Huang, J Yang, Z Chiang, S Chen, J Liu… - Cell Death & …, 2022 - nature.com
Mesenchymal stem cells (MSCs) can be widely isolated from various tissues including bone
marrow, umbilical cord, and adipose tissue, with the potential for self-renewal and …
marrow, umbilical cord, and adipose tissue, with the potential for self-renewal and …
A paradigm shift in cell-free approach: the emerging role of MSCs-derived exosomes in regenerative medicine
S Moghadasi, M Elveny, HS Rahman… - Journal of translational …, 2021 - Springer
Recently, mesenchymal stem/stromal cells (MSCs) due to their pro-angiogenic, anti-
apoptotic, and immunoregulatory competencies along with fewer ethical issues are …
apoptotic, and immunoregulatory competencies along with fewer ethical issues are …
The role of MSC in wound healing, scarring and regeneration
R Guillamat-Prats - Cells, 2021 - mdpi.com
Tissue repair and regeneration after damage is not completely understood, and current
therapies to support this process are limited. The wound healing process is associated with …
therapies to support this process are limited. The wound healing process is associated with …
Recent applications of immunomodulatory biomaterials for disease immunotherapy
Immunotherapy is used to regulate systemic hyperactivation or hypoactivation to treat
various diseases. Biomaterial‐based immunotherapy systems can improve therapeutic …
various diseases. Biomaterial‐based immunotherapy systems can improve therapeutic …
Inhalable dry powder mRNA vaccines based on extracellular vesicles
Respiratory diseases are a global burden, with millions of deaths attributed to pulmonary
illnesses and dysfunctions. Therapeutics have been developed, but they present major …
illnesses and dysfunctions. Therapeutics have been developed, but they present major …
Mesenchymal stem cell-derived exosomes and other extracellular vesicles as new remedies in the therapy of inflammatory diseases
CR Harrell, N Jovicic, V Djonov, N Arsenijevic… - Cells, 2019 - mdpi.com
There is growing evidence that mesenchymal stem cell (MSC)-based immunosuppression
was mainly attributed to the effects of MSC-derived extracellular vesicles (MSC-EVs). MSC …
was mainly attributed to the effects of MSC-derived extracellular vesicles (MSC-EVs). MSC …
Mesenchymal stem/stromal cell-derived exosomes for immunomodulatory therapeutics and skin regeneration
DH Ha, H Kim, J Lee, HH Kwon, GH Park, SH Yang… - Cells, 2020 - mdpi.com
Exosomes are nano-sized vesicles that serve as mediators for cell-to-cell communication.
With their unique nucleic acids, proteins, and lipids cargo compositions that reflect the …
With their unique nucleic acids, proteins, and lipids cargo compositions that reflect the …
Immunomodulatory and regenerative effects of mesenchymal stem cells and extracellular vesicles: therapeutic outlook for inflammatory and degenerative diseases
S Dabrowska, A Andrzejewska, M Janowski… - Frontiers in …, 2021 - frontiersin.org
Mesenchymal stem cells (MSCs) are non-hematopoietic, multipotent stem cells derived from
mesoderm, which can be easily isolated from many sources such as bone marrow, umbilical …
mesoderm, which can be easily isolated from many sources such as bone marrow, umbilical …
Extracellular vesicles derived from mesenchymal stem cells (MSC) in regenerative medicine: applications in skin wound healing
A Casado-Díaz, JM Quesada-Gómez… - … in Bioengineering and …, 2020 - frontiersin.org
The cells secrete extracellular vesicles (EV) that may have an endosomal origin, or from
evaginations of the plasma membrane. The former are usually called exosomes, with sizes …
evaginations of the plasma membrane. The former are usually called exosomes, with sizes …
Mesenchymal stem cells reverse EMT process through blocking the activation of NF-κB and Hedgehog pathways in LPS-induced acute lung injury
K Xiao, W He, W Guan, F Hou, P Yan, J Xu… - Cell death & …, 2020 - nature.com
Acute lung injury (ALI) is a pulmonary disorder, which can result in fibrosis of the lung
tissues. Recently, mesenchymal stem cell (MSC) has become a novel therapeutic method …
tissues. Recently, mesenchymal stem cell (MSC) has become a novel therapeutic method …