[HTML][HTML] The microbiome as a potential target for therapeutic manipulation in pancreatic cancer

R Abdul Rahman, A Lamarca, RA Hubner, JW Valle… - Cancers, 2021 - mdpi.com
Simple Summary Pancreatic cancer is one of the most lethal cancers. It is a difficult cancer to
treat, and the complexity surrounding the pancreatic tumour is one of the contributing factors …

[HTML][HTML] Recent pre-clinical advancements in nuclear medicine: pioneering the path to a limitless future

W Echavidre, D Fagret, M Faraggi, V Picco… - Cancers, 2023 - mdpi.com
Simple Summary This review summarizes recent advances in the nuclear medicine
theranostic approach. It covers the repurposing of historical radiotracers for new indications …

[HTML][HTML] Cell surface GRP78-directed CAR-T cells are effective at treating human pancreatic cancer in preclinical models

Y Yuan, J Fan, D Liang, S Wang, X Luo, Y Zhu… - Translational …, 2024 - Elsevier
Pancreatic cancer is a highly lethal solid malignancy with limited treatment options. Chimeric
antigen receptor T (CAR-T) cell therapy has been successfully applied to treat hematological …

[HTML][HTML] Imaging PARP with [18F]rucaparib in pancreatic cancer models

CY Chan, Z Chen, G Destro, M Veal, D Lau… - European Journal of …, 2022 - Springer
Purpose Rucaparib, an FDA-approved PARP inhibitor, is used as a single agent in
maintenance therapy to provide promising treatment efficacy with an acceptable safety …

[HTML][HTML] Overview and future perspectives on tumor-targeted positron emission tomography and fluorescence imaging of pancreatic cancer in the era of neoadjuvant …

MA van Dam, FA Vuijk, JA Stibbe, RD Houvast… - Cancers, 2021 - mdpi.com
Simple Summary Patients diagnosed with pancreatic cancer have a poor prognosis at time
of diagnosis, with a 5-year survival rate of merely 10%. The only treatment with curative …

[HTML][HTML] Molecular targeted positron emission tomography imaging and radionuclide therapy of pancreatic ductal adenocarcinoma

TT Poels, FA Vuijk, LF de Geus-Oei, AL Vahrmeijer… - Cancers, 2021 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis,
mainly due to difficulty in early detection of the disease by current imaging modalities. In this …

[HTML][HTML] The expression and survival significance of sodium glucose transporters in pancreatic cancer

J Du, J Gu, J Deng, L Kong, Y Guo, C Jin, Y Bao, D Fu… - BMC cancer, 2022 - Springer
Abstract Background Sodium glucose transporters (SGLTs) play vital roles in glucose uptake
in many solid cancers, including pancreatic cancer (PC). However, their expression profile in …

Theranostics: Timing is Everything

JH Turner - Cancer Biotherapy & Radiopharmaceuticals, 2024 - liebertpub.com
On stage, and in real life, timing is critical for success. Theranostic cancer care epitomizes
the central role of timing in the evolution of efficacious molecular targeted radioligand …

Vacuolar protein sorting 35 (VPS35) acts as a tumor promoter via facilitating cell cycle progression in pancreatic ductal adenocarcinoma

Y Gai, L Qian, S Jiang, J Li, X Zhang, X Yang… - Functional & Integrative …, 2023 - Springer
Pancreatic ductal adenocarcinoma (PDAC) is insidious and highly malignant with extremely
poor prognosis and drug resistance to current chemotherapies. Therefore, there is a critical …

[HTML][HTML] MRI-Based Tumor Necrosis Depiction in Pancreatic Ductal Adenocarcinoma: Can It Predict Tumor Aggressiveness?

MA Anderson, DE Knipp, Y Noda, SC Kamran… - Cancers, 2023 - mdpi.com
Simple Summary Pancreatic adenocarcinoma is a leading cause of cancer related deaths
worldwide. Since surgical treatment involves serious risk and morbidity, guiding patients …