Revisiting the theoretical and methodological foundations of depression measurement
Depressive disorders are among the leading causes of global disease burden, but there has
been limited progress in understanding the causes of and treatments for these disorders. In …
been limited progress in understanding the causes of and treatments for these disorders. In …
[HTML][HTML] Canalization and plasticity in psychopathology
RL Carhart-Harris, S Chandaria, DE Erritzoe… - …, 2023 - Elsevier
This theoretical article revives a classical bridging construct, canalization, to describe a new
model of a general factor of psychopathology. To achieve this, we have distinguished …
model of a general factor of psychopathology. To achieve this, we have distinguished …
Studying mental health problems as systems, not syndromes
EI Fried - Current Directions in Psychological Science, 2022 - journals.sagepub.com
Despite decades of clinical, sociopolitical, and research efforts, progress in understanding
and treating mental health problems remains disappointing. I discuss two barriers that have …
and treating mental health problems remains disappointing. I discuss two barriers that have …
A critical evaluation of the p-factor literature
The p-factor is a construct that is thought to explain and maybe even cause variation in all
forms of psychopathology. Since its 'discovery'in 2012, hundreds of studies have been …
forms of psychopathology. Since its 'discovery'in 2012, hundreds of studies have been …
[PDF][PDF] Advancing the network theory of mental disorders: A computational model of panic disorder
The network theory of psychopathology posits that mental disorders are complex systems of
mutually reinforcing symptoms. This overarching framework has proven highly generative …
mutually reinforcing symptoms. This overarching framework has proven highly generative …
[HTML][HTML] Intervening on psychopathology networks: Evaluating intervention targets through simulations
G Lunansky, J Naberman, CD van Borkulo, C Chen… - Methods, 2022 - Elsevier
Identifying the different influences of symptoms in dynamic psychopathology models may
hold promise for increasing treatment efficacy in clinical applications. Dynamic …
hold promise for increasing treatment efficacy in clinical applications. Dynamic …
A critical evaluation of QIDS-SR-16 using data from a trial of psilocybin therapy versus escitalopram treatment for depression
B Weiss, D Erritzoe, B Giribaldi… - Journal of …, 2023 - journals.sagepub.com
Background: In a recent clinical trial examining the comparative efficacy of psilocybin
therapy (PT) versus escitalopram treatment (ET) for major depressive disorder, 14 of 16 …
therapy (PT) versus escitalopram treatment (ET) for major depressive disorder, 14 of 16 …
Attractor landscapes: A unifying conceptual model for understanding behaviour change across scales of observation
Models and theories in behaviour change science are not in short supply, but they almost
exclusively pertain to a particular facet of behaviour, such as automaticity or reasoned …
exclusively pertain to a particular facet of behaviour, such as automaticity or reasoned …
Rising early warning signals in affect associated with future changes in depression: a dynamical systems approach
JE Curtiss, D Mischoulon, LB Fisher, C Cusin… - Psychological …, 2023 - cambridge.org
Background Predicting future states of psychopathology such as depressive episodes has
been a hallmark initiative in mental health research. Dynamical systems theory has …
been a hallmark initiative in mental health research. Dynamical systems theory has …
[HTML][HTML] Do We Need a Novel Framework for Classifying Psychopathology? A Discussion Paper
Method As examples of the new approaches that have emerged, here we introduce the
Hierarchical Taxonomy of Psychopathology (HiTOP), the Research Domain Criteria (RDoC) …
Hierarchical Taxonomy of Psychopathology (HiTOP), the Research Domain Criteria (RDoC) …