Background. Activated immediate early genes (IEGs) play key roles in mediating cellular
response after ischemia/reperfusion (I/R) injuries in some organs such as liver, heart and …

Objective: Brief episodes of ischemia of 20 min or less have the potential to protect the heart.
Such episodes are associated primarily with reversible ischemic injury yet they induce …

Neovascularization, the natural physiological process of formation of new blood vessels, is
extremely important for ameliorating the function of the heart that undergoes ischemic stress …

Heme oxygenase (HO) isozymes, HO-1 and HO-2 catalyze the cleavage of heme b to form
the antioxidant biliverdin IXa, iron and the putative cellular messenger carbon monoxide …

The in vitro aging of human fibroblasts has become a classical model for studying cellular
aging. This model was lately redefined by showing that these cells represent a stem cell …

Since the completion of the Human Genome Project and the advent of the large scaled
unbiased '‐omics' techniques, the field of systems biology has emerged. Systems biology …

Handbook of Growth Factors, Volume III is devoted to hematopoiesis and its regulation by
endogenous factors with growth stimulatory and growth inhibitory properties. The book …

Citrinin (CTN) is a fungal secondary metabolite that contaminates various foodstuffs and
animal feeds; it also exhibits organotoxicity in several animal models. In this study, the …

Myocardial hibernation represents a condition of regional ventricular dysfunction in patients
with chronic coronary artery disease, which reverses gradually after revascularization. The …

Despite improvements in treatment, myocardial infarction (MI) remains an important cause of
morbidity and mortality. Inflammation arising from ischaemic and reperfusion injury is a key …