The activation of stress-activated protein (SAP) kinase may lead to an induction of apoptosis
that is responsible for part of the cardiomyocyte death in reperfusion injury. The objective of …

Objective: Our previous studies have suggested a role of mitogen-activated protein kinases
(MAPKs) in cardioprotection in the porcine heart. To investigate, whether this could be due …

Publisher Summary This chapter describes data that highlight the significance of apoptotic
cardiomyocyte death in cardiac development and during ischemia and reperfusion. There …

Protein kinase C (PKC) has been implicated in the preconditioning-induced cardiac
protection in ischemic/reperfused myocardium. We studied the effect of PKC inhibition with …

We have generated a mouse model for hepatic ischemia in which surgical subcutaneous
transposition of the spleen allows hepatic ischemia to be applied without affecting other …

Early growth response‐(Egr‐) 1 is an upstream master switch in controlling inflammatory
responses following myocardial ischemia‐reperfusion (I/R). Activation of extracellular signal …

Objective: Protection of the myocardium against ischemia/reperfusion injury is a major
challenge in cardiac surgery and cardiology. A cardioprotective role of heat shock proteins …

We investigated the mitochondrial gene expression related to cardiac function and
ventricular fibrillation (VF) in ischemic/reperfused nondiabetic and diabetic myocardium. To …

Acute myocardial ischemia initiates a cascade of cellular events that lead to irreversible
injury. We previously described the transient nature of heat‐shock induced cardioprotection; …