Bacterial pathogens as causative agents of infection constitute an alarming concern in the
public health sector. In particular, bacteria with resistance to multiple antimicrobial agents …

Quorum sensing is a cell-to-cell communication system that exists widely in the microbiome
and is related to cell density. The high-density colony population can generate a sufficient …

Genomes of all living organisms are constantly threatened by endogenous and exogenous
agents that challenge the chemical integrity of DNA. Most bacteria have evolved a …

In recent year, propagation and resistance of pathogenic microorganisms (bacteria, fungi
and virals) to common antimicrobial agents has led to serious health and food problems …

Antibiotic resistance is one of the major challenges facing modern medicine worldwide. The
past few decades have witnessed rapid progress in our understanding of the multiple factors …

The alarmones guanosine tetraphosphate and guanosine pentaphosphate (collectively
referred to as (p) ppGpp) are involved in regulating growth and several different stress …

Bacterial biofilms are associated with a wide range of infections, from those related to
exogenous devices, such as catheters or prosthetic joints, to chronic tissue infections such …

Microorganisms grouped together into spatially-organized communities called biofilms, are
the cause of dramatic chronic infections in plants, animals and humans. In this review, the …

Aminoglycoside (AG) antibiotics are used to treat many Gram-negative and some Gram-
positive infections and, importantly, multidrug-resistant tuberculosis. Among various …

Quinolone antibiotics represent one of the most important classes of anti-infective agents
and, although still clinically valuable, their use has been compromised by the increasing …