The global pandemic of drug-sensitive cancers and the increasing threat from drug-resistant
cancers make an urgent need to develop more effective anti-cancer candidates. Quinolone …

Indole alkaloids, which are abundant in nature, are a significant source of pharmacologically
active compounds. Indole alkaloids have the potential to exert anticancer activity via various …

While natural products have undoubtedly played a pivotal role in drug discovery, their
potential as lead compounds has been hindered by challenges such as limited accessibility …

Indole alkaloids are an important group of natural products in the plant kingdom for their
diversity structures and significant biological effects on human health. The genus Melodinus …

Continued interest in bioactive alkaloids led to the isolation of four undescribed alkaloids
along with 74 known ones from the aerial parts of Tabernaemontana bufalina Lour. The …

Covering: since early reports up to the end of 2020 This review presents a complete
coverage of the mavacuranes alkaloids since early reports till date. Mavacuranes alkaloids …

Abstract Melodinus cochinchinensis (Lour.) Merr. has been used in Traditional Chinese
Medicine for the management of various ailments, yet its chemical constituents are rarely …

The Melodinus species have been proved to be good resources of bisindole alkaloids. Six
bisindole alkaloids were isolated from the leaves and stems of Melodinus cochinchinensis …

Although the main bishydroxylated long-term metabolite of the WADA-banned anabolic
agent ligandrol (LGD-4033) is an important metabolic marker, it is not readily available in …

Enantioselective dearomatization inverse-electron-demand Diels–Alder reaction/oxidation
of indoles with 2-(2-nitrovinyl)-1, 4-benzoquinone was realised using a chiral …