Role of somatostatin signalling in neuroendocrine tumours

O Rogoza, K Megnis, M Kudrjavceva… - International Journal of …, 2022 - mdpi.com
Somatostatin (SST) is a small peptide that exerts inhibitory effects on a wide range of
neuroendocrine cells. Due to the fact that somatostatin regulates cell growth and hormone …

[HTML][HTML] Epigenetic regulation in gastroenteropancreatic neuroendocrine tumors

JS Crabtree - Frontiers in Oncology, 2022 - frontiersin.org
Gastroenteropancreatic neuroendocrine neoplasms are a rare, diverse group of
neuroendocrine tumors that form in the pancreatic and gastrointestinal tract, and often …

[HTML][HTML] Circulating hsa-miR-5096 predicts 18F-FDG PET/CT positivity and modulates somatostatin receptor 2 expression: a novel miR-based assay for pancreatic …

M Bocchini, M Tazzari, S Ravaioli, F Piccinini… - Frontiers in …, 2023 - frontiersin.org
Gastro-entero-pancreatic neuroendocrine tumors (GEP-NETs) are rare diseases
encompassing pancreatic (PanNETs) and ileal NETs (SINETs), characterized by …

CD47 expression and CD163+ macrophages correlated with prognosis of pancreatic neuroendocrine tumor

R Imam, Q Chang, M Black, C Yu, W Cao - BMC cancer, 2021 - Springer
Background Recent studies have suggested the important roles of CD47 and tumor-
associated macrophages in the prognosis and immunotherapy of various human …

Gender differences in pancreatic neuroendocrine neoplasms: A retrospective study based on the population of Hubei Province, China

M Fu, L Yu, L Yang, Y Chen, X Chen, Q Hu… - Frontiers in …, 2022 - frontiersin.org
Objective The aims of the present study were to investigate gender differences in the
clinicopathological features, distant metastasis and prognosis of pancreatic neuroendocrine …

Diagnostic management of gastroenteropancreatic neuroendocrine neoplasms: technique optimization and tips and tricks for radiologists

F Pellegrino, V Granata, R Fusco, F Grassi, S Tafuto… - Tomography, 2023 - mdpi.com
Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) comprise a
heterogeneous group of neoplasms, which derive from cells of the diffuse neuroendocrine …

Prognostic role of hERG1 potassium channels in neuroendocrine tumours of the ileum and pancreas

J Iorio, L Antonuzzo, E Scarpi, M D'Amico… - International Journal of …, 2022 - mdpi.com
hERG1 potassium channels are widely expressed in human cancers of different origins,
where they affect several key aspects of cellular behaviour. The present study was designed …

[HTML][HTML] Liquid biopsy and preclinical tools for advancing diagnosis and treatment of patients with pancreatic neuroendocrine neoplasms

B Smolkova, A Kataki, J Earl, I Ruz-Caracuel… - Critical Reviews in …, 2022 - Elsevier
Pancreatic neuroendocrine neoplasms (pNENs) are rare cancers with broad challenges for
their management. The main clinical obstacles are the high rate of patients diagnosed at …

MiRNA Expression in Neuroendocrine Neoplasms of Frequent Localizations

A Korotaeva, D Mansorunov, N Apanovich… - Non-coding RNA, 2021 - mdpi.com
Neuroendocrine neoplasms (NEN) are infrequent malignant tumors of a neuroendocrine
nature that arise in various organs. They occur most frequently in the lungs, intestines …

Combined deletion of MEN1, ATRX and PTEN triggers development of high-grade pancreatic neuroendocrine tumors in mice

ME Fuentes, X Lu, NM Flores, S Hausmann… - Scientific Reports, 2024 - nature.com
Pancreatic neuroendocrine tumors (PanNETs) are a heterogeneous group of tumors that
exhibit an unpredictable and broad spectrum of clinical presentations and biological …