Role of somatostatin signalling in neuroendocrine tumours

O Rogoza, K Megnis, M Kudrjavceva… - International Journal of …, 2022 - mdpi.com
Somatostatin (SST) is a small peptide that exerts inhibitory effects on a wide range of
neuroendocrine cells. Due to the fact that somatostatin regulates cell growth and hormone …

[HTML][HTML] Liquid biopsy and preclinical tools for advancing diagnosis and treatment of patients with pancreatic neuroendocrine neoplasms

B Smolkova, A Kataki, J Earl, I Ruz-Caracuel… - Critical Reviews in …, 2022 - Elsevier
Pancreatic neuroendocrine neoplasms (pNENs) are rare cancers with broad challenges for
their management. The main clinical obstacles are the high rate of patients diagnosed at …

Diagnostic management of gastroenteropancreatic neuroendocrine neoplasms: technique optimization and tips and tricks for radiologists

F Pellegrino, V Granata, R Fusco, F Grassi, S Tafuto… - Tomography, 2023 - mdpi.com
Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) comprise a
heterogeneous group of neoplasms, which derive from cells of the diffuse neuroendocrine …

Circulating hsa-miR-5096 predicts 18F-FDG PET/CT positivity and modulates somatostatin receptor 2 expression: a novel miR-based assay for pancreatic …

M Bocchini, M Tazzari, S Ravaioli, F Piccinini… - Frontiers in …, 2023 - frontiersin.org
Gastro-entero-pancreatic neuroendocrine tumors (GEP-NETs) are rare diseases
encompassing pancreatic (PanNETs) and ileal NETs (SINETs), characterized by …

The Quest for Circulating Biomarkers in Neuroendocrine Neoplasms: a Clinical Perspective

L Mariën, O Islam, S Chhajlani, W Lybaert… - … Treatment Options in …, 2023 - Springer
Opinion statement Given the considerable heterogeneity in neuroendocrine neoplasms
(NENs), it appears unlikely that a sole biomarker exists capable of fully capturing all useful …

Gender differences in pancreatic neuroendocrine neoplasms: A retrospective study based on the population of Hubei Province, China

M Fu, L Yu, L Yang, Y Chen, X Chen, Q Hu… - Frontiers in …, 2022 - frontiersin.org
Objective The aims of the present study were to investigate gender differences in the
clinicopathological features, distant metastasis and prognosis of pancreatic neuroendocrine …

CD47 expression and CD163+ macrophages correlated with prognosis of pancreatic neuroendocrine tumor

R Imam, Q Chang, M Black, C Yu, W Cao - BMC cancer, 2021 - Springer
Background Recent studies have suggested the important roles of CD47 and tumor-
associated macrophages in the prognosis and immunotherapy of various human …

Prognostic value of tumor-to-parenchymal contrast enhancement ratio on portal venous-phase CT in pancreatic neuroendocrine neoplasms

HJ Park, HJ Kim, JH Kim, SY Kim, SH Choi, JH Byun… - European …, 2023 - Springer
Objectives We aimed to evaluate the prognostic value of tumor-to-parenchymal contrast
enhancement ratio on portal venous-phase CT (CER on PVP) and compare its prognostic …

S100 protein expression in primary and metastatic Neuroendocrine Neoplasms: A specific marker of Pancreatic origin

MA Pepper, BW Dulken, Y Wang… - The American Journal …, 2024 - journals.lww.com
Neuroendocrine neoplasms can arise in a wide variety of anatomic sites including the
gastrointestinal tract, pancreas, and lung, among others. Here, we report on the expression …

Epigenetic regulation in gastroenteropancreatic neuroendocrine tumors

JS Crabtree - Frontiers in Oncology, 2022 - frontiersin.org
Gastroenteropancreatic neuroendocrine neoplasms are a rare, diverse group of
neuroendocrine tumors that form in the pancreatic and gastrointestinal tract, and often …