Lung cancer 2020: epidemiology, etiology, and prevention

BC Bade, CSD Cruz - Clinics in chest medicine, 2020 - chestmed.theclinics.com
Notable changes in lung cancer epidemiology and prevention have occurred over the past
decade owing to changes in smoking patterns, groundbreaking advances in our …

Lung cancer: epidemiology, etiology, and prevention

CSD Cruz, LT Tanoue… - Clinics in chest …, 2011 - chestmed.theclinics.com
Lung cancer is the leading cause of cancer death in the United States and around the world.
Almost as many Americans die of lung cancer every year than die of prostate, breast, and …

Comorbidities of COPD

A Cavaillès, G Brinchault-Rabin… - European …, 2013 - Eur Respiratory Soc
By 2020, chronic obstructive pulmonary disease (COPD) will be the third cause of mortality.
Extrapulmonary comorbidities influence the prognosis of patients with COPD. Tobacco …

“Sentinel” circulating tumor cells allow early diagnosis of lung cancer in patients with chronic obstructive pulmonary disease

M Ilie, V Hofman, E Long-Mira, E Selva, JM Vignaud… - PloS one, 2014 - journals.plos.org
Chronic obstructive pulmonary disease (COPD) is a risk factor for lung cancer. Migration of
circulating tumor cells (CTCs) into the blood stream is an early event that occurs during …

Mechanistic links between COPD and lung cancer

AMG Houghton - Nature Reviews Cancer, 2013 - nature.com
Numerous epidemiological studies have consistently linked the presence of chronic
obstructive pulmonary disease (COPD) to the development of lung cancer, independently of …

Epithelial–mesenchymal transition, a spectrum of states: role in lung development, homeostasis, and disease

MK Jolly, C Ward, MS Eapen, S Myers… - Developmental …, 2018 - Wiley Online Library
Epithelial–mesenchymal transition (EMT) plays key roles during lung development and
many lung diseases such as chronic obstructive pulmonary disease (COPD), lung cancer …

Immune evolution from preneoplasia to invasive lung adenocarcinomas and underlying molecular features

H Dejima, X Hu, R Chen, J Zhang, J Fujimoto… - Nature …, 2021 - nature.com
The mechanism by which anti-cancer immunity shapes early carcinogenesis of lung
adenocarcinoma (ADC) is unknown. In this study, we characterize the immune contexture of …

Chronic obstructive pulmonary disease and comorbidities

M Decramer, W Janssens - The Lancet Respiratory Medicine, 2013 - thelancet.com
Results of epidemiological studies have shown that chronic obstructive pulmonary disease
(COPD) is frequently associated with comorbidities, the most serious and prevalent being …

Inflammation in chronic obstructive pulmonary disease and its role in cardiovascular disease and lung cancer

PT King - Clinical and translational medicine, 2015 - Springer
Chronic obstructive pulmonary disease (COPD) is characterized by lung inflammation that
persists after smoking cessation. This inflammation is heterogeneous but the key …

Glucocorticoid receptor triggers a reversible drug-tolerant dormancy state with acquired therapeutic vulnerabilities in lung cancer

S Prekovic, K Schuurman, I Mayayo-Peralta… - Nature …, 2021 - nature.com
The glucocorticoid receptor (GR) regulates gene expression, governing aspects of
homeostasis, but is also involved in cancer. Pharmacological GR activation is frequently …