The triad of nanotechnology, cell signalling, and scaffold implantation for the successful repair of damaged organs: An overview on soft-tissue engineering
P Abdollahiyan, F Oroojalian… - Journal of controlled …, 2021 - Elsevier
As a milestone in therapeutic fields, tissue engineering has offered an alternative strategy to
address unmet clinical needs for the repair and replacement of human damaged organs …
address unmet clinical needs for the repair and replacement of human damaged organs …
Adverse cardiovascular effects and potential molecular mechanisms of DEHP and its metabolites—a review
ZJ Wen, ZY Wang, YF Zhang - Science of The Total Environment, 2022 - Elsevier
Currently, cardiovascular disease (CVD) is a health hazard that is associated with
progressive deterioration upon exposure to environmental pollutants. Di (2-ethylhexyl) …
progressive deterioration upon exposure to environmental pollutants. Di (2-ethylhexyl) …
[HTML][HTML] Utility of iPSC-derived cells for disease modeling, drug development, and cell therapy
MW Nicholson, CY Ting, DZH Chan, YC Cheng… - Cells, 2022 - mdpi.com
The advent of induced pluripotent stem cells (iPSCs) has advanced our understanding of the
molecular mechanisms of human disease, drug discovery, and regenerative medicine. As …
molecular mechanisms of human disease, drug discovery, and regenerative medicine. As …
Effects of electrically conductive nano-biomaterials on regulating cardiomyocyte behavior for cardiac repair and regeneration
Myocardial infarction (MI) represents one of the most prevalent cardiovascular diseases,
with a highly relevant and impactful role in public health. Despite the therapeutic advances …
with a highly relevant and impactful role in public health. Despite the therapeutic advances …
Why translation from basic discoveries to clinical applications is so difficult for atrial fibrillation and possible approaches to improving it
Atrial fibrillation (AF) is the most common sustained clinical arrhythmia, with a lifetime
incidence of up to 37%, and is a major contributor to population morbidity and mortality …
incidence of up to 37%, and is a major contributor to population morbidity and mortality …
[HTML][HTML] Modeling hypertrophic cardiomyopathy with human cardiomyocytes derived from induced pluripotent stem cells
J Li, X Feng, X Wei - Stem Cell Research & Therapy, 2022 - Springer
One of the obstacles in studying the pathogenesis of hypertrophic cardiomyopathy (HCM) is
the poor availability of myocardial tissue samples at the early stages of disease …
the poor availability of myocardial tissue samples at the early stages of disease …
Development and characterization of furfuryl-gelatin electrospun scaffolds for cardiac tissue engineering
In this study, three types of electrospun scaffolds, including furfuryl-gelatin (f-gelatin) alone, f-
gelatin with polycaprolactone (PCL) in a 1: 1 ratio, and coaxial scaffolds with PCL (core) and …
gelatin with polycaprolactone (PCL) in a 1: 1 ratio, and coaxial scaffolds with PCL (core) and …
Cellular interplay between cardiomyocytes and non-myocytes in diabetic cardiomyopathy
RJ Phang, RH Ritchie, DJ Hausenloy… - Cardiovascular …, 2023 - academic.oup.com
Patients with Type 2 diabetes mellitus (T2DM) frequently exhibit a distinctive cardiac
phenotype known as diabetic cardiomyopathy. Cardiac complications associated with T2DM …
phenotype known as diabetic cardiomyopathy. Cardiac complications associated with T2DM …
[HTML][HTML] Advances in 3D organoid models for stem cell-based cardiac regeneration
M Martin, EKN Gähwiler, M Generali… - International Journal of …, 2023 - mdpi.com
The adult human heart cannot regain complete cardiac function following tissue injury,
making cardiac regeneration a current clinical unmet need. There are a number of clinical …
making cardiac regeneration a current clinical unmet need. There are a number of clinical …
Deciphering pathogenicity of variants of uncertain significance with CRISPR-edited iPSCs
Genetic variants play an important role in conferring risk for cardiovascular diseases (CVDs).
With the rapid development of next-generation sequencing (NGS), thousands of genetic …
With the rapid development of next-generation sequencing (NGS), thousands of genetic …