Background Biliary atresia (BA) is the most common cause of obstructive jaundice in infants.
Although the Kasai procedure has greatly improved the prognosis, most patients still need …

Biliary Atresia, a common basis for neonatal cholestasis and primary indication for Liver
Transplantation, accounts for 60% of pediatric Liver Transplantations. While the …

Background/purpose The role of serum gamma-glutamyl transpeptidase (GGT) levels in
predicting clinical outcomes after Kasai portoenterostomy (KPE) is unknown. This study …

Background We desired to observe the changes of transforming growth factor-β1/drosophila
mothers against decapentaplegic protein (TGF-β1/Smad3) signaling pathway in the …

Background/Aims: Biliary Atresia (BA) is a devastating pediatric liver disease and
characterized by aggressive liver fibrosis progression. The Interleukin-33 (IL-33)/ST2 …

Background. Biliary atresia (BA) is a devastating congenital disease characterized by
inflammation and progressive liver fibrosis. Activation of hepatic stellate cells (HSCs) plays a …

Background Pathogenesis of progressive liver fibrosis in biliary atresia after successful
portoenterostomy remains unclear. We related hepatic expression of transforming growth …

Activation of hepatic stellate cells (HSCs) plays a pivotal role in the development of liver
fibrosis. C1q/tumor necrosis factor-related protein 3 (CTRP3), a member of CTRPs, was …

Pediatric liver disease (PLD) is a major cause of severe morbidity and prolonged
hospitalizations in children. Stratifying patients in terms of prognosis remains challenging …

The objective of this study was to observe the distribution of macrophages (MPs) expressing
transforming growth factor beta-1 (TGF-β1) in tissue samples from patients with different …