The definition of unexplained infertility: a systematic review

C Raperport, J Desai, D Qureshi… - … Journal of Obstetrics …, 2024 - Wiley Online Library
Background There is no consensus on tests required to either diagnose unexplained
infertility or use for research inclusion criteria. This leads to heterogeneity and bias affecting …

[HTML][HTML] Should IUI replace IVF as first-line treatment for unexplained infertility? A literature review

JKY Man, AE Parker, S Broughton, H Ikhlaq… - BMC Women's Health, 2023 - Springer
Background Unexplained infertility accounts for 25% of infertility causes in the UK. Active
intervention methods, such as intrauterine insemination (IUI) or in vitro fertilisation (IVF), are …

[HTML][HTML] The prevalence of endometriosis in patients with unexplained infertility

C Nezhat, F Khoyloo, A Tsuei, E Armani… - Journal of Clinical …, 2024 - mdpi.com
Endometriosis, a systemic ailment, profoundly affects various aspects of life, often eluding
detection for over a decade. This leads to enduring issues such as chronic pain, infertility …

[HTML][HTML] Seasonal Serum 25 (OH) Vitamin D Level and Reproductive or Immune Markers in Reproductive-Aged Women with Infertility: A Cross-Sectional …

K Ota, J Mitsui, S Katsumata, Y Takayanagi, Y Nako… - Nutrients, 2023 - mdpi.com
Several studies have reported that vitamin D may modify human reproductive functions;
however, the results are conflicting. We aimed to comprehensively evaluate serum vitamin D …

Guideline for unexplained couple infertility: misunderstandings on the approach to the male factor

G Grande, A Graziani, A Ferlin - Human Reproduction, 2024 - academic.oup.com
We read with interest the guideline about unexplained infertility developed by the Guideline
Group (GDG) on Unexplained Infertility of ESHRE (Romualdi et al., 2023). We appreciated …

Seminal Oxidative Stress and Sperm DNA Fragmentation in Men from Couples with Infertility or Unexplained Recurrent Pregnancy Loss

JMK Rasmussen, MIR Dalgaard, H Alipour… - Journal of Clinical …, 2024 - mdpi.com
(1) Background: This case–control study examined whether men from couples with
unexplained recurrent pregnancy loss (RPL) or infertility exhibited higher seminal oxidative …

[HTML][HTML] To Test or Not to Test: Routine Thrombophilia Diagnostic Screening of Women with Reproductive Failures

U Wysocka, K Sałacińska, I Pinkier… - Journal of Clinical …, 2023 - mdpi.com
Background: Recurrent reproductive failure is a global health issue affecting a significant
number of women. Thrombophilias have been implicated as a possible cause. Inherited …

[HTML][HTML] Oxidative Imbalance in Endometriosis-Related Infertility—The Therapeutic Role of Antioxidants

I Dymanowska-Dyjak, K Frankowska… - International Journal of …, 2024 - mdpi.com
Endometriosis in half of affected women is closely related to problems with fertility.
Endometriosis-associated infertility is caused by a wide range of abnormalities affecting the …

Evaluating prognosis in unexplained infertility

LS Au, Q Feng, L Shingshetty, A Maheshwari, BW Mol - Fertility and Sterility, 2024 - Elsevier
Importance The diagnosis of unexplained infertility presents a dilemma as it signifies both
uncertainty about the cause of infertility and the potential for natural conception. Immediate …

Prognosis-based management of unexplained infertility—why not?

L Shingshetty, R Wang, Q Feng… - Human …, 2024 - academic.oup.com
Up to a half of couples seeking medical assistance for infertility are diagnosed with
unexplained infertility, characterized by normal ovulation, tubal patency, and semen analysis …