Uterine leiomyomata (UL) have a substantial impact on women's health, but relatively few
studies have identified opportunities for primary prevention of these neoplasms. Most …

BACKGROUND Uterine leiomyoma (also known as fibroid or myoma) is the most common
benign tumor of the uterus found in women of reproductive age. It is not usually fatal but can …

BACKGROUND Endometriosis is recognized as a steroid-dependent disorder; however, the
precise roles of nuclear receptors (NRs) in steroid responsiveness and other signaling …

Uterine fibroids (also known as leiomyomas or myomas) are the most common form of
benign uterine tumors. Clinical presentations include abnormal bleeding, pelvic masses …

Objective To investigate the efficacy and safety of repeated 12-week courses of 5 or 10 mg
daily ulipristal acetate for intermittent treatment of symptomatic uterine fibroids. Design …

Uterine fibroids (leiomyomas or myomas), benign monoclonal tumors, are the most common
benign tumors in women. Heavy or prolonged menstrual bleeding, abnormal uterine …

Highlights•Both estradiol and progesterone are essential for uterine fibroid
development.•Ovarian blockade arrests leiomyoma growth, but it has many side …

Selective progesterone receptor modulators (SPRMs) are a new class of compounds
developed to target the progesterone receptor (PR) with a mix of agonist and antagonist …

Endometriosis is defined as endometrial-like tissue outside the uterine cavity. It is a chronic
inflammatory estrogen-dependent disease causing pain and infertility in about 10% of …

Background Pictorial blood loss assessment charts (PBACs) represent the most widely used
method to assess menstrual blood loss (MBL) in clinical trials. The aims of this review were …