[HTML][HTML] Marine natural products: A source of novel anticancer drugs
Cancer remains one of the most lethal diseases worldwide. There is an urgent need for new
drugs with novel modes of action and thus considerable research has been conducted for …
drugs with novel modes of action and thus considerable research has been conducted for …
[HTML][HTML] Marine natural products
Covering: 2016. Previous review: Nat. Prod. Rep., 2017, 34, 235–294 This review covers the
literature published in 2016 for marine natural products (MNPs), with 757 citations (643 for …
literature published in 2016 for marine natural products (MNPs), with 757 citations (643 for …
[HTML][HTML] Software tools and approaches for compound identification of LC-MS/MS data in metabolomics
The annotation of small molecules remains a major challenge in untargeted mass
spectrometry-based metabolomics. We here critically discuss structured elucidation …
spectrometry-based metabolomics. We here critically discuss structured elucidation …
Identification of small molecules using accurate mass MS/MS search
Tandem mass spectral library search (MS/MS) is the fastest way to correctly annotate MS/MS
spectra from screening small molecules in fields such as environmental analysis, drug …
spectra from screening small molecules in fields such as environmental analysis, drug …
Cheminformatics in natural product‐based drug discovery
Y Chen, J Kirchmair - Molecular Informatics, 2020 - Wiley Online Library
This review seeks to provide a timely survey of the scope and limitations of cheminformatics
methods in natural product‐based drug discovery. Following an overview of data resources …
methods in natural product‐based drug discovery. Following an overview of data resources …
[HTML][HTML] The essentials of marine biotechnology
Coastal countries have traditionally relied on the existing marine resources (eg, fishing,
food, transport, recreation, and tourism) as well as tried to support new economic endeavors …
food, transport, recreation, and tourism) as well as tried to support new economic endeavors …
[HTML][HTML] Marine-derived pharmaceuticals–challenges and opportunities
U Lindequist - Biomolecules & therapeutics, 2016 - ncbi.nlm.nih.gov
Marine biosphere is the largest one of the earth and harbors an enormous number of
different organisms. Living conditions differ fundamentally from those in terrestrial …
different organisms. Living conditions differ fundamentally from those in terrestrial …
Advancements in capturing and mining mass spectrometry data are transforming natural products research
Covering: 2016 up to 2021 Mass spectrometry (MS) is an essential technology in natural
products research with MS fragmentation (MS/MS) approaches becoming a key tool. Recent …
products research with MS fragmentation (MS/MS) approaches becoming a key tool. Recent …
Current status and contemporary approaches to the discovery of antitumor agents from higher plants
G Agarwal, PJB Carcache, EM Addo… - Biotechnology advances, 2020 - Elsevier
Higher plant constituents have afforded clinically available anticancer drugs. These include
both chemically unmodified small molecules and their synthetic derivatives currently used or …
both chemically unmodified small molecules and their synthetic derivatives currently used or …
[HTML][HTML] Computational methodologies in the exploration of marine natural product leads
F Pereira, J Aires-de-Sousa - Marine drugs, 2018 - mdpi.com
Computational methodologies are assisting the exploration of marine natural products
(MNPs) to make the discovery of new leads more efficient, to repurpose known MNPs, to …
(MNPs) to make the discovery of new leads more efficient, to repurpose known MNPs, to …