Antiphospholipid syndrome

K Schreiber, S Sciascia, PG De Groot… - Nature reviews Disease …, 2018 - nature.com
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by the presence
of antiphospholipid antibodies, such as lupus anticoagulant, anticardiolipin antibodies and …

Pathogenesis and management of antiphospholipid syndrome

DRJ Arachchillage, M Laffan - British journal of haematology, 2017 - Wiley Online Library
Antiphospholipid antibodies are a heterogeneous group of autoantibodies that have clear
associations with thrombosis and pregnancy morbidity, and which together constitute the …

[HTML][HTML] Laboratory criteria for antiphospholipid syndrome: communication from the SSC of the ISTH

KMJ Devreese, TL Ortel, V Pengo, B De Laat - Journal of thrombosis and …, 2018 - Elsevier
Currently, we use the classification criteria for antiphospholipid syndrome (APS) formulated
during the consensus conference in Sapporo and revised in Sydney 1. Classification criteria …

[PDF][PDF] Pathogenic autoreactive T and B cells cross-react with mimotopes expressed by a common human gut commensal to trigger autoimmunity

WE Ruff, C Dehner, WJ Kim, O Pagovich, CL Aguiar… - Cell host & …, 2019 - cell.com
Given the immense antigenic load present in the microbiome, we hypothesized that
microbiota mimotopes can be a persistent trigger in human autoimmunity via cross-reactivity …

[HTML][HTML] IgG/IgM antiphospholipid antibodies present in the classification criteria for the antiphospholipid syndrome: a critical review of their association with …

H Kelchtermans, L Pelkmans, B De Laat… - Journal of thrombosis …, 2016 - Elsevier
Essentials• The clinical value of IgM antibodies in thrombotic antiphospholipid syndrome
(APS) is debated.• By review of literature, we reconsidered the clinical value of IgM …

Antiphospholipid antibody testing and standardization

KMJ Devreese - International journal of laboratory hematology, 2014 - Wiley Online Library
The laboratory criteria that define patients with antiphospholipid syndrome (APS) include
lupus anticoagulant (LAC), anticardiolipin antibodies and anti‐β2 glycoprotein I antibodies …

[HTML][HTML] Role of anti‐domain 1‐β2glycoprotein I antibodies in the diagnosis and risk stratification of antiphospholipid syndrome

AS De Craemer, J Musial, KMJ Devreese - Journal of thrombosis and …, 2016 - Elsevier
Essentials• Antibodies to domain 1 of β 2 glycoprotein I (aD1) are a subset of
antiphospholipid antibodies.• We evaluated the added diagnostic value of an automated …

How to interpret antiphospholipid laboratory tests

KMJ Devreese - Current Rheumatology Reports, 2020 - Springer
Abstract Purpose of the Review This review focuses on the laboratory tests necessary for the
diagnosis of antiphospholipid syndrome (APS). For the interpretation of the results of the …

Testing for antiphospholipid antibodies: Advances and best practices

KMJ Devreese - International Journal of Laboratory …, 2020 - Wiley Online Library
The diagnosis of antiphospholipid syndrome (APS) relies on the detection of circulating
antiphospholipid antibodies (aPL). Currently, lupus anticoagulant (LAC), anticardiolipin …

Anti–Domain I β2-Glycoprotein I Antibodies and Activated Protein C Resistance Predict Thrombosis in Antiphospholipid Syndrome: TAC(I)T Study

S Zuily, B de Laat, F Guillemin… - The journal of …, 2020 - academic.oup.com
Background Antibodies binding to domain I of β2-glycoprotein I (aDI) and activated protein C
(APC) resistance are associated with an increased risk of thrombosis in cross-sectional …