Entosis: the core mechanism and crosstalk with other cell death programs
S Kim, D Lee, SE Kim, M Overholtzer - Experimental & Molecular …, 2024 - nature.com
Cell death pathways play critical roles in organism development and homeostasis as well as
in the pathogenesis of various diseases. While studies over the last decade have elucidated …
in the pathogenesis of various diseases. While studies over the last decade have elucidated …
The role of competing endogenous RNA network in the development of hepatocellular carcinoma: potential therapeutic targets
Z Tang, X Li, Y Zheng, J Liu, C Liu, X Li - Frontiers in Cell and …, 2024 - frontiersin.org
The current situation of hepatocellular carcinoma (HCC) management is challenging due to
its high incidence, mortality, recurrence and metastasis. Recent advances in gene genetic …
its high incidence, mortality, recurrence and metastasis. Recent advances in gene genetic …
[HTML][HTML] Heterogeneous ferroptosis susceptibility of macrophages caused by focal iron overload exacerbates rheumatoid arthritis
Y Liu, X Luo, Y Chen, J Dang, D Zeng, X Guo, W Weng… - Redox Biology, 2024 - Elsevier
Focal iron overload is frequently observed in patients with rheumatoid arthritis (RA), yet its
functional significance remains elusive. Herein, we report that iron deposition in lesion …
functional significance remains elusive. Herein, we report that iron deposition in lesion …
Cell death in cancer chemotherapy using taxanes
AP Xu, LB Xu, ER Smith, JS Fleishman… - Frontiers in …, 2024 - frontiersin.org
Cancer cells evolve to be refractory to the intrinsic programmed cell death mechanisms,
which ensure cellular tissue homeostasis in physiological conditions. Chemotherapy using …
which ensure cellular tissue homeostasis in physiological conditions. Chemotherapy using …
Arnicolide D induces endoplasmic reticulum stress-mediated oncosis via ATF4 and CHOP in hepatocellular carcinoma cells
YS Lin, Z Sun, LS Shen, RH Gong, JW Chen, Y Xu… - Cell Death …, 2024 - nature.com
Endoplasmic reticulum (ER) stress can trigger various cell death mechanisms beyond
apoptosis, providing promise in cancer treatment. Oncosis, characterized by cellular …
apoptosis, providing promise in cancer treatment. Oncosis, characterized by cellular …
Programmed cell death in tumor immunity: mechanistic insights and clinical implications
M Wang, F Yu, Y Zhang, P Li - Frontiers in Immunology, 2024 - frontiersin.org
Programmed cell death (PCD) is an evolutionarily conserved mechanism of cell suicide that
is controlled by various signaling pathways. PCD plays an important role in a multitude of …
is controlled by various signaling pathways. PCD plays an important role in a multitude of …
[HTML][HTML] Gut microbiota-generated metabolites: missing puzzles to hosts' health, diseases, and aging
The gut microbiota, an intricate community of bacteria residing in the gastrointestinal system,
assumes a pivotal role in various physiological processes. Beyond its function in food …
assumes a pivotal role in various physiological processes. Beyond its function in food …
Jiangqi Pingxiao formula regulates dendritic cell apoptosis in an autophagy-dependent manner through the AMPK/mTOR pathway in a murine model of OVA-induced …
Y Shan, J Wu, X Dai, C Yuan, J Jiang, H Yan… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Allergic asthma is a recurring respiratory condition that
typically manifests during childhood or adolescence. It is characterized by a dominant type II …
typically manifests during childhood or adolescence. It is characterized by a dominant type II …
Advances in Cell‐Rich Inks for Biofabricating Living Architectures
J Almeida‐Pinto, BS Moura, VM Gaspar… - Advanced …, 2024 - Wiley Online Library
Advancing biofabrication toward manufacturing living constructs with well‐defined
architectures and increasingly biologically relevant cell densities is highly desired to mimic …
architectures and increasingly biologically relevant cell densities is highly desired to mimic …
Programmed cell death: NINJ1 and mechanisms of plasma membrane rupture
S Ramos, E Hartenian, P Broz - Trends in Biochemical Sciences, 2024 - cell.com
Lytic cell death culminates in cell swelling and plasma membrane rupture (PMR). The
cellular contents released, including proteins, metabolites, and nucleic acids, can act as …
cellular contents released, including proteins, metabolites, and nucleic acids, can act as …