[HTML][HTML] CircRNAs in colorectal cancer: potential biomarkers and therapeutic targets
Y Zhang, J Luo, W Yang, WC Ye - Cell death & disease, 2023 - nature.com
Globally, colorectal cancer (CRC) is the third most prevalent cancer and the second leading
cause of cancer-related deaths. Circular RNAs (circRNAs) are single-stranded RNA with …
cause of cancer-related deaths. Circular RNAs (circRNAs) are single-stranded RNA with …
[HTML][HTML] Circular RNAs in breast cancer diagnosis, treatment and prognosis
X Huang, C Song, J Zhang, L Zhu, H Tang - Oncology Research, 2024 - ncbi.nlm.nih.gov
Breast cancer has surpassed lung cancer to become the most common malignancy
worldwide. The incidence rate and mortality rate of breast cancer continue to rise, which …
worldwide. The incidence rate and mortality rate of breast cancer continue to rise, which …
[HTML][HTML] Dissection of FOXO1-induced LYPLAL1-DT impeding triple-negative breast cancer progression via mediating hnRNPK/β-catenin complex
Y Tang, W Tian, S Zheng, Y Zou, J Xie, J Zhang, X Li… - Research, 2023 - spj.science.org
Triple-negative breast cancer (TNBC) is considered as the most hazardous subtype of
breast cancer owing to its accelerated progression, enormous metastatic potential, and …
breast cancer owing to its accelerated progression, enormous metastatic potential, and …
New approaches for targeting PCSK9: small-interfering ribonucleic acid and genome editing
RF Oostveen, AV Khera, S Kathiresan… - … , and vascular biology, 2023 - Am Heart Assoc
There is overwhelming clinical and genetic evidence supporting the concept that low-density-
lipoprotein cholesterol should be as low as possible for as long as possible in patients at …
lipoprotein cholesterol should be as low as possible for as long as possible in patients at …
[HTML][HTML] MiRNAs and lncRNAs in the regulation of innate immune signaling
I Gareev, ME Ramirez, E Goncharov, D Ivliev… - Non-coding RNA …, 2023 - Elsevier
The detection and defense against foreign agents and pathogens by the innate immune
system is a crucial mechanism in the body. A comprehensive understanding of the signaling …
system is a crucial mechanism in the body. A comprehensive understanding of the signaling …
[HTML][HTML] Extracellular vesicles for therapeutic nucleic acid delivery: loading strategies and challenges
A Oshchepkova, M Zenkova, V Vlassov - International Journal of …, 2023 - mdpi.com
Extracellular vesicles (EVs) are membrane vesicles released into the extracellular milieu by
cells of various origins. They contain different biological cargoes, protecting them from …
cells of various origins. They contain different biological cargoes, protecting them from …
A novel MYCN-YTHDF1 cascade contributes to retinoblastoma tumor growth by eliciting m6A -dependent activation of multiple oncogenes
Y Luo, M He, J Yang, F Zhang, J Chen, X Wen… - Science China Life …, 2023 - Springer
Retinoblastoma, the most prevalent primary intraocular tumor in children, leads to vision
impairment, disability and even death. In addition to RB1 inactivation, MYCN activation has …
impairment, disability and even death. In addition to RB1 inactivation, MYCN activation has …
[HTML][HTML] LP (a): structure, genetics, associated cardiovascular risk, and emerging therapeutics
Lipoprotein (a)[Lp (a)] is a molecule bound to apolipoprotein (a) with some similarity to low-
density lipoprotein cholesterol (LDL-C), which has been found to be a risk factor for …
density lipoprotein cholesterol (LDL-C), which has been found to be a risk factor for …
LncFASA promotes cancer ferroptosis via modulating PRDX1 phase separation
X Fan, F Liu, X Wang, Y Wang, Y Chen, C Shi… - Science China Life …, 2024 - Springer
Ferroptosis, a unique type of non-apoptotic cell death resulting from iron-dependent lipid
peroxidation, has a potential physiological function in tumor suppression, but its underlying …
peroxidation, has a potential physiological function in tumor suppression, but its underlying …
[HTML][HTML] Navigating the landscape of RNA delivery systems in cardiovascular disease therapeutics
Cardiovascular diseases (CVDs) stand as the leading cause of death worldwide, posing a
significant global health challenge. Consequently, the development of innovative …
significant global health challenge. Consequently, the development of innovative …