Traumatic brain injury (TBI) remains one of the leading causes of morbidity and mortality
amongst civilians and military personnel globally. Despite advances in our knowledge of the …

All components of the CNS are surrounded by a diffuse extracellular matrix (ECM)
containing chondroitin sulphate proteoglycans (CSPGs), heparan sulphate proteoglycans …

Neuroinflammation and mitochondrial dysfunction are common features of chronic
neurodegenerative diseases of the central nervous system. Both conditions can lead to …

Surgical repair of severe peripheral nerve injuries represents not only a pressing medical
need, but also a great clinical challenge. Autologous nerve grafting remains a golden …

▪ Abstract Nerve regeneration is a complex biological phenomenon. In the peripheral
nervous system, nerves can regenerate on their own if injuries are small. Larger injuries …

Spinal cord injury (SCI) is a disabling condition that disrupts motor, sensory, and autonomic
functions. Despite extensive research in the last decades, SCI continues to be a global …

Covering: up to 2010 This review focuses on recent developments in the use of natural
products as therapeutics for Alzheimer's disease. The compounds span a diverse array of …

Neuronal plasticity in the brain is greatly enhanced during critical periods early in life and
was long thought to be rather limited thereafter. Studies in primary sensory areas of the …

Carbohydrate-carrying molecules in the nervous system have important roles during
development, regeneration and synaptic plasticity. Carbohydrates mediate interactions …

Traumatic damage to the central nervous system (CNS) destroys the blood–brain barrier
(BBB) and provokes the invasion of hematogenous cells into the neural tissue. Invading …