[HTML][HTML] Chrysin: Perspectives on contemporary status and future possibilities as pro-health agent
M Stompor-Gorący, A Bajek-Bil, M Machaczka - Nutrients, 2021 - mdpi.com
Chrysin belongs to the group of natural polyphenols. It can be found, among others, in
honey, propolis and fruits and has a wide range of biological activities, including the …
honey, propolis and fruits and has a wide range of biological activities, including the …
A comprehensive and current review on the role of flavonoids in lung cancer–Experimental and theoretical approaches
Background It is well-known that flavonoids, which can be easily obtained from many fruits
and vegetables are widely preferred in the treatment of some important diseases. Some …
and vegetables are widely preferred in the treatment of some important diseases. Some …
Halogenated baicalein as a promising antiviral agent toward SARS-CoV-2 main protease
K Hengphasatporn, P Wilasluck… - Journal of Chemical …, 2022 - ACS Publications
The coronavirus disease pandemic is a constant reminder that global citizens are in
imminent danger of exposure to emerging infectious diseases. Therefore, developing a …
imminent danger of exposure to emerging infectious diseases. Therefore, developing a …
Designing Potent α-Glucosidase Inhibitors: A Synthesis and QSAR Modeling Approach for Biscoumarin Derivatives
THT Phan, K Hengphasatporn, Y Shigeta, W Xie… - ACS …, 2023 - ACS Publications
Nineteen biscoumarins were synthesized, well-characterized, and evaluated against α-
glucosidases in vitro. Of these, six compounds (10, 12, 16, and 17–19) were newly …
glucosidases in vitro. Of these, six compounds (10, 12, 16, and 17–19) were newly …
Modification of flavonoids: Methods and influences on biological activities
Flavonoids are important active ingredients in plant-based food, which have many beneficial
effects on health. But the low solubility, poor oral bioavailability, and inferior stability of many …
effects on health. But the low solubility, poor oral bioavailability, and inferior stability of many …
Discussion on the structural modification and anti-tumor activity of flavonoids
ZG Zhou, DD Li, Y Chen, X Chen… - Current Topics in …, 2022 - ingentaconnect.com
Flavonoids are secondary metabolites of plants. In general# 140; most flavonoids are
combined with glucosides and have extremely complex molecular structures. In nature …
combined with glucosides and have extremely complex molecular structures. In nature …
[HTML][HTML] Structural investigation of interactions between halogenated flavonoids and the lipid membrane along with their role as cytotoxic agents
This study focuses on understanding the structural and molecular changes in lipid
membranes under the influence of six halogenated flavonoid derivatives differing in the …
membranes under the influence of six halogenated flavonoid derivatives differing in the …
[HTML][HTML] Designing multi-target-directed flavonoids: a strategic approach to Alzheimer's disease
The underlying causes of Alzheimer's disease (AD) remain a mystery, with multiple
pathological components, including oxidative stress, acetylcholinesterase, amyloid-β, and …
pathological components, including oxidative stress, acetylcholinesterase, amyloid-β, and …
Improvement of the solubility and anticancer activity of 6, 8-dibromochrysin by encapsulation into β-cyclodextrin and its derivatives
K Kerdpol, A Oo, P Mahalapbutr, D Todsaporn… - Journal of the Taiwan …, 2023 - Elsevier
Abstract Background 6, 8-dibromochrysin (BrCN), a halogenated chrysin, possesses a
profound bioactivity against dengue and Zika viruses and various types of cancer. However …
profound bioactivity against dengue and Zika viruses and various types of cancer. However …
[HTML][HTML] A promiscuous halogenase for the derivatization of flavonoids
D Kolling, M Stierhof, C Lasch, M Myronovskyi… - Molecules, 2021 - mdpi.com
Halogenation often improves the bioactive properties of natural products and is used in
pharmaceutical research for the generation of new potential drug leads. High regio-and …
pharmaceutical research for the generation of new potential drug leads. High regio-and …