The apportionment of human diversity revisited
Objectives Studies of the apportionment of human genetic diversity have found that local
populations harbor nearly as much diversity as the species as a whole. These studies have …
populations harbor nearly as much diversity as the species as a whole. These studies have …
Whole mitogenomes reveal that NW Africa has acted both as a source and a destination for multiple human movements
J Aizpurua-Iraola, A Abdeli, T Benhassine, F Calafell… - Scientific Reports, 2023 - nature.com
Despite being enclosed between the Mediterranean Sea and the Sahara Desert, North
Africa has been the scenario of multiple human migrations that have shaped the genetic …
Africa has been the scenario of multiple human migrations that have shaped the genetic …
The deep population history in Africa
N Hollfelder, G Breton, P Sjödin… - Human Molecular …, 2021 - academic.oup.com
Africa is the continent with the greatest genetic diversity among humans and the level of
diversity is further enhanced by incorporating non-majority groups, which are often …
diversity is further enhanced by incorporating non-majority groups, which are often …
Genome-wide genotype and sequence-based reconstruction of the 140,000 year history of modern human ancestry
D Shriner, F Tekola-Ayele, A Adeyemo, CN Rotimi - Scientific reports, 2014 - nature.com
We investigated ancestry of 3,528 modern humans from 163 samples. We identified 19
ancestral components, with 94.4% of individuals showing mixed ancestry. After using whole …
ancestral components, with 94.4% of individuals showing mixed ancestry. After using whole …
MaLAdapt Reveals Novel Targets of Adaptive Introgression From Neanderthals and Denisovans in Worldwide Human Populations
Adaptive introgression (AI) facilitates local adaptation in a wide range of species. Many state-
of-the-art methods detect AI with ad-hoc approaches that identify summary statistic outliers …
of-the-art methods detect AI with ad-hoc approaches that identify summary statistic outliers …
Genomic analyses of human European diversity at the southwestern edge: isolation, African influence and disease associations in the Canary Islands
B Guillen-Guio, JM Lorenzo-Salazar… - Molecular Biology …, 2018 - academic.oup.com
Despite the genetic resemblance of Canary Islanders to other southern European
populations, their geographical isolation and the historical admixture of aborigines (from …
populations, their geographical isolation and the historical admixture of aborigines (from …
Genomic evidence for shared common ancestry of East African hunting-gathering populations and insights into local adaptation
LB Scheinfeldt, S Soi, C Lambert… - Proceedings of the …, 2019 - National Acad Sciences
Anatomically modern humans arose in Africa∼ 300,000 years ago, but the demographic
and adaptive histories of African populations are not well-characterized. Here, we have …
and adaptive histories of African populations are not well-characterized. Here, we have …
The Arab genome: health and wealth
H Zayed - Gene, 2016 - Elsevier
The 22 Arab nations have a unique genetic structure, which reflects both conserved and
diverse gene pools due to the prevalent endogamous and consanguineous marriage culture …
diverse gene pools due to the prevalent endogamous and consanguineous marriage culture …
The peopling of the last Green Sahara revealed by high-coverage resequencing of trans-Saharan patrilineages
E D'Atanasio, B Trombetta, M Bonito, A Finocchio… - Genome biology, 2018 - Springer
Background Little is known about the peopling of the Sahara during the Holocene climatic
optimum, when the desert was replaced by a fertile environment. Results In order to …
optimum, when the desert was replaced by a fertile environment. Results In order to …
Human OMICs and computational biology research in Africa: current challenges and prospects
Following the publication of the first human genome, OMICs research, including genomics,
transcriptomics, proteomics, and metagenomics, has been on the rise. OMICs studies …
transcriptomics, proteomics, and metagenomics, has been on the rise. OMICs studies …