Generation of induced pluripotent stem (iPS) cells by nuclear reprogramming

D Dey, GRD Evans - Stem Cells International, 2011 - Wiley Online Library
During embryonic development pluripotency is progressively lost irreversibly by cell division,
differentiation, migration and organ formation. Terminally differentiated cells do not generate …

Full-term development of gaur–bovine interspecies somatic cell nuclear transfer embryos: effect of trichostatin A treatment

K Srirattana, S Imsoonthornruksa… - … " Cloning and Stem …, 2012 - liebertpub.com
Trichostatin A (TSA) has previously been used in somatic cell nuclear transfer (SCNT) to
improve the cloning efficiency in several species, which led our team to investigate the …

Histone Demethylase KDM4D Could Improve the Developmental Competence of Buffalo (Bubalus Bubalis) Somatic Cell Nuclear Transfer (SCNT) Embryos

Y Feng, X Zhao, Z Li, C Luo, Z Ruan… - Microscopy and …, 2021 - academic.oup.com
Somatic cell nuclear transfer (SCNT) holds vast potential in agriculture. However, its
applications are still limited by its low efficiency. Histone 3 lysine 9 trimethylation (H3K9me3) …

HDAC1/DNMT3A-containing complex is associated with suppression of Oct4 in cervical cancer cells

D Liu, P Zhou, L Zhang, W Gong, G Huang… - Biochemistry …, 2012 - Springer
Octamer-binding transcription factor 4 (Oct4), an important embryonic transcriptional factor,
is highly expressed in several tumors and is considered as a hallmark of cancer stem cells …

Zinc improves the developmental ability of bovine in vitro fertilization embryos through its antioxidative action

Y Feng, X Zhao, Z Ruan, Z Li, H Mo, F Lu, D Shi - Theriogenology, 2024 - Elsevier
Zinc, an essential trace mineral, exerts a pivotal influence in various biological processes.
Through zinc concentration analysis, we found that the zinc concentration in the bovine …

Treatment with small molecules is an important milestone towards the induction of pluripotency in neural stem cells derived from human cord blood

I Szablowska-Gadomska, J Sypecka, V Zayat… - Acta Neurobiologiae …, 2012 - ane.pl
Standardization of methods for obtaining iPS cells from the human somatic cells and then
their successful differentiation are important in the context of their possible application in …

PXD101 significantly improves nuclear reprogramming and the in vitro developmental competence of porcine SCNT embryos

JX Jin, JD Kang, S Li, L Jin, HY Zhu, Q Guo… - Biochemical and …, 2015 - Elsevier
In this study, we investigated the effects of the histone deacetylase inhibitor PXD101
(belinostat) on the preimplantation development of porcine somatic cell nuclear transfer …

Use of trichostatin A alters the expression of HDAC3 and KAT2 and improves in vitro development of bovine embryos cloned using less methylated mesenchymal …

CG Silva, CF Martins, HC Bessler… - … in Domestic Animals, 2019 - Wiley Online Library
Contents The aim of this work was to investigate the methylation and hydroxymethylation
status of mesenchymal stem cells (MSC) from amniotic fluid (MSC‐AF), adipose tissue (MSC …

Nuclear dynamics of histone H3 trimethylated on lysine 9 and/or phosphorylated on serine 10 in mouse cloned embryos as new markers of reprogramming?

K Ribeiro-Mason, C Boulesteix, V Brochard… - … " Cloning and Stem …, 2012 - liebertpub.com
Somatic cell nuclear transfer (SCNT) is the injection of a donor nucleus into an enucleated
egg. Despite the use of this technology for many years in research, it is still quite inefficient …

Trichostatin A improves preimplantation development of bovine cloned embryos and alters expression of epigenetic and pluripotency genes in cloned blastocysts

HJ Oh, TH Lee, JH Lee, BC Lee - Journal of Veterinary Medical …, 2012 - jstage.jst.go.jp
We investigated the effects of exposure time and concentration of trichostatin A (TSA) on in
vitro development and quality of bovine SCNT embryos. At multiple time points, the relative …