[HTML][HTML] Chlamydiae in the environment

A Collingro, S Köstlbacher, M Horn - Trends in Microbiology, 2020 - cell.com
Chlamydiae have been known for more than a century as major pathogens of humans. Yet
they are also found ubiquitously in the environment where they thrive within protists and in …

[HTML][HTML] Engineering of obligate intracellular bacteria: progress, challenges and paradigms

EE McClure, ASO Chávez, DK Shaw… - Nature Reviews …, 2017 - nature.com
It is estimated that approximately one billion people are at risk of infection with obligate
intracellular bacteria, but little is known about the underlying mechanisms that govern their …

[HTML][HTML] Pangenomics reveals alternative environmental lifestyles among chlamydiae

S Köstlbacher, A Collingro, T Halter, F Schulz… - Nature …, 2021 - nature.com
Chlamydiae are highly successful strictly intracellular bacteria associated with diverse
eukaryotic hosts. Here we analyzed metagenome-assembled genomes of the “Genomes …

A Chlamydia effector combining deubiquitination and acetylation activities induces Golgi fragmentation

JN Pruneda, RJ Bastidas, E Bertsoulaki… - Nature …, 2018 - nature.com
Pathogenic bacteria are armed with potent effector proteins that subvert host signalling
processes during infection. The activities of bacterial effectors and their associated roles …

[HTML][HTML] Clear victory for chlamydia: the subversion of host innate immunity

H Chen, Y Wen, Z Li - Frontiers in microbiology, 2019 - frontiersin.org
As obligate intracellular bacterial pathogens, members of the Chlamydia genera are the
pivotal triggers for a wide range of infections, which can lead to blinding trachoma, pelvic …

[HTML][HTML] The functional ClpXP protease of Chlamydia trachomatis requires distinct clpP genes from separate genetic loci

S Pan, IT Malik, D Thomy, B Henrichfreise, P Sass - Scientific reports, 2019 - nature.com
Clp proteases play a central role in bacterial physiology and, for some bacterial species, are
even essential for survival. Also due to their conservation among bacteria including …

[HTML][HTML] Advances in genetic manipulation of Chlamydia trachomatis

W Wan, D Li, D Li, J Jiao - Frontiers in Immunology, 2023 - frontiersin.org
Chlamydia trachomatis, one species of Chlamydia spp., has the greatest impact on human
health and is the main cause of bacterial sexually transmitted diseases and preventable …

[HTML][HTML] Th1 cells are dispensable for primary clearance of Chlamydia from the female reproductive tract of mice

JA Rixon, CE Depew, SJ McSorley - PLoS pathogens, 2022 - journals.plos.org
Protective immune responses to Chlamydia infection within the female reproductive tract
(FRT) are incompletely understood. MHC class II-restricted CD4 Th1 responses are believed …

Global prevalence of chlamydial infections in birds: A systematic review and meta-analysis

P Sukon, NH Nam, P Kittipreeya, A Sara-In… - Preventive Veterinary …, 2021 - Elsevier
Chamydia species are bacterial pathogens that can infect a wide range of animal hosts
including humans. In birds, Chlamydia psittaci is a leading cause of chlamydial infections …

[PDF][PDF] Host cell death during infection with Chlamydia: a double-edged sword

BS Sixt - FEMS Microbiology Reviews, 2021 - academic.oup.com
The phylum Chlamydiae constitutes a group of obligate intracellular bacteria that infect a
remarkably diverse range of host species. Some representatives are significant pathogens …