Ulcerative colitis: making the diagnosis

T Kaenkumchorn, G Wahbeh - Gastroenterology Clinics, 2020 - gastro.theclinics.com
The diagnosis of ulcerative colitis (UC) is based on clinical symptoms and signs including
hematochezia and urgency, endoscopic evaluation, and histologic parameters in the …

Assessing severity of disease in patients with ulcerative colitis

BS Pabla, DA Schwartz - Gastroenterology Clinics, 2020 - gastro.theclinics.com
Ulcerative colitis (UC) is a chronic disease that can present at various stages of disease
activity and severity. Depending on disease activity at any moment and the overall severity …

ACG clinical guideline: ulcerative colitis in adults

DT Rubin, AN Ananthakrishnan… - Official journal of the …, 2019 - journals.lww.com
Ulcerative colitis (UC) is an idiopathic inflammatory disorder. These guidelines indicate the
preferred approach to the management of adults with UC and represent the official practice …

Clinical use of anti-TNF therapy and increased risk of infections

T Ali, S Kaitha, S Mahmood, A Ftesi… - Drug, healthcare and …, 2013 - Taylor & Francis
Biologics such as antitumor necrosis factor (anti-TNF) drugs have emerged as important
agents in the treatment of many chronic inflammatory diseases, especially in cases …

Infections due to dysregulated immunity: an emerging complication of cancer immunotherapy

T Morelli, K Fujita, G Redelman-Sidi, PT Elkington - Thorax, 2022 - thorax.bmj.com
Immune checkpoint inhibitors (ICIs) have revolutionised cancer treatment. However, immune-
related adverse events (irAEs) are a common side effect which can mimic infection …

[HTML][HTML] Cytomegalovirus: pathogen, paradigm, and puzzle

M Boeckh, AP Geballe - The Journal of clinical investigation, 2011 - Am Soc Clin Investig
Human cytomegalovirus (CMV), one of the eight herpesviruses that commonly infect
humans, is best known for its propensity to cause disease in immunocompromised patients …

Fecal Microbiota Transplantation is Safe and Efficacious for Recurrent or Refractory Clostridium difficile Infection in Patients with Inflammatory Bowel Disease

M Fischer, D Kao, C Kelly, A Kuchipudi… - Inflammatory bowel …, 2016 - academic.oup.com
Background New treatments are needed as Clostridium difficile infection (CDI) is becoming
increasingly formidable. Fecal microbiota transplantation (FMT) has a 90% success rate in …

The role of oxidative and inflammatory stress and persistent viral infections in immunosenescence

ME Bauer, M De la Fuente - Mechanisms of ageing and development, 2016 - Elsevier
Immunosenescence involves age-related remodeling changes in the organization of
lymphoid organs and functionality of immune cells, which have been associated with …

[HTML][HTML] Human cytomegalovirus and autoimmune diseases: where are we?

F Gugliesi, S Pasquero, G Griffante, S Scutera… - Viruses, 2021 - mdpi.com
Human cytomegalovirus (HCMV) is a ubiquitous double-stranded DNA virus belonging to
the β-subgroup of the herpesvirus family. After the initial infection, the virus establishes …

Cytomegalovirus load in inflamed intestinal tissue is predictive of resistance to immunosuppressive therapy in ulcerative colitis

X Roblin, S Pillet, A Oussalah, P Berthelot… - Official journal of the …, 2011 - journals.lww.com
OBJECTIVES: Previous studies have suggested an association between cytomegalovirus
(CMV) infection and steroid-refractory inflammatory bowel disease. In this study, the use of …