Antiepileptic drugs and liver disease

J Vidaurre, S Gedela, S Yarosz - Pediatric Neurology, 2017 - Elsevier
Acute, symptomatic seizures or epilepsy may complicate the course of hepatic disease.
Choosing the most appropriate antiepileptic drug in this setting represents a difficult …

Carbamazepine adverse drug reactions

I Fricke-Galindo, A LLerena, H Jung-Cook… - Expert review of …, 2018 - Taylor & Francis
Introduction: Carbamazepine (CBZ) is used for the treatment of epilepsy and other
neurological and psychiatric disorders. The occurrence of adverse reactions (ADRs) to CBZ …

Эпилепсия у детей и взрослых женщин и мужчин

ВА Карлов - 2019 - elibrary.ru
В руководстве представлены результаты 60-летней работы автора в области детской
и взрослой неврологии и эпилептологии. Впервые эпилептология представлена в …

Postmarketing experience with brivaracetam in the treatment of epilepsies: a multicenter cohort study from Germany

I Steinig, F von Podewils, G Möddel, S Bauer… - …, 2017 - Wiley Online Library
Objective To evaluate factors predicting efficacy, retention, and tolerability of add‐on
brivaracetam (BRV) in clinical practice. Methods A multicenter, retrospective cohort study …

Antiepileptic drugs as analgesics/adjuvants in inflammatory pain: current preclinical evidence

M Tomić, U Pecikoza, A Micov, S Vučković… - Pharmacology & …, 2018 - Elsevier
Inflammatory pain is the most common type of pain that is treated clinically. The use of
currently available treatments (classic analgesics-NSAIDs, paracetamol and opioids) is …

In vitro effects of eslicarbazepine (S‐licarbazepine) as a potential precision therapy on SCN8A variants causing neuropsychiatric disorders

E Bayraktar, Y Liu, L Sonnenberg… - British Journal of …, 2023 - Wiley Online Library
Background and Purpose Variants in SCN8A, the NaV1. 6 channel's coding gene, are
characterized by a variety of symptoms, including intractable epileptic seizures, psychomotor …

Pooled efficacy and safety of eslicarbazepine acetate as add‐on treatment in patients with focal‐onset seizures: Data from four double‐blind placebo‐controlled …

C Elger, M Koepp, E Trinka… - CNS Neuroscience …, 2017 - Wiley Online Library
Purpose Pooled evaluation of the key efficacy and safety profile of eslicarbazepine acetate
(ESL) added‐on to stable antiepileptic therapy in adults with focal‐onset seizures. Methods …

Selecting rational drug combinations in epilepsy

B Abou-Khalil - Cns Drugs, 2017 - Springer
Monotherapy remains the standard initial therapy of epilepsy, but when the first antiepileptic
drug (AED) fails, combination therapy may be considered. The choice of combination …

Safety profile of eslicarbazepine acetate as add-on therapy in adults with refractory focal-onset seizures: from clinical studies to 6 years of post-marketing experience

H Gama, M Vieira, R Costa, J Graça, LM Magalhães… - Drug Safety, 2017 - Springer
Introduction Eslicarbazepine acetate was first approved in the European Union in 2009 as
adjunctive therapy in adults with partial-onset seizures with or without secondary …

Clinical pharmacology and therapeutics of antiepileptic drugs for treatment of epilepsy and seizure disorders

DS Reddy - International Journal of Pharmaceutical Sciences and …, 2020 - ijpsnonline.com
This article describes clinical antiepileptic drugs (AEDs) that are available for treatment of
epilepsy. Epilepsy is characterized by repeated occurrence of seizures. Epileptic seizures …