Overcoming colloidal nanoparticle aggregation in biological milieu for cancer therapeutic delivery: Perspectives of materials and particle design
SH Lim, TW Wong, WX Tay - Advances in Colloid and Interface Science, 2024 - Elsevier
Nanoparticles as cancer therapeutic carrier fail in clinical translation due to complex
biological environments in vivo consisting of electrolytes and proteins which render …
biological environments in vivo consisting of electrolytes and proteins which render …
Targeting chronic myeloid leukemia stem/progenitor cells using venetoclax-loaded immunoliposome
Simple Summary Chronic myeloid leukemia stem cells (CML LSCs) are a rare and
quiescent population that are resistant to tyrosine kinase inhibitors. CML LSCs have many …
quiescent population that are resistant to tyrosine kinase inhibitors. CML LSCs have many …
Catalytic Neutralization of water pollutants mediated by dendritic polymers
Radially polymerized dendritic compounds are nowadays an established polymer category
next to their linear, branched, and cross-linked counterparts. Their uncommon tree-like …
next to their linear, branched, and cross-linked counterparts. Their uncommon tree-like …
Nanoparticle delivery platforms for RNAi therapeutics targeting COVID-19 disease in the respiratory tract
Since December 2019, a pandemic of COVID-19 disease, caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly spread across the globe. At …
respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly spread across the globe. At …
Dysregulated signalling pathways driving anticancer drug resistance
N Bou Antoun, AM Chioni - International Journal of Molecular Sciences, 2023 - mdpi.com
One of the leading causes of death worldwide, in both men and women, is cancer. Despite
the significant development in therapeutic strategies, the inevitable emergence of drug …
the significant development in therapeutic strategies, the inevitable emergence of drug …
Bactericidal properties of rod-, peanut-, and star-shaped gold nanoparticles coated with ceragenin CSA-131 against multidrug-resistant bacterial strains
SJ Chmielewska, K Skłodowski, J Depciuch, P Deptuła… - Pharmaceutics, 2021 - mdpi.com
Background: The ever-growing number of infections caused by multidrug-resistant (MDR)
bacterial strains requires an increased effort to develop new antibiotics. Herein, we …
bacterial strains requires an increased effort to develop new antibiotics. Herein, we …
Effects of Gold Nanoparticles Functionalized with Bioactive Compounds from Cornus mas Fruit on Aorta Ultrastructural and Biochemical Changes in Rats on a …
Cornus mas L. extract (CM) presents hypolipidemic, antioxidant and anti-inflammatory
activity. Gold nanoparticles (AuNPs) are considered potent delivery systems and may be …
activity. Gold nanoparticles (AuNPs) are considered potent delivery systems and may be …
Recent advances in ocular drug delivery systems and targeting VEGF receptors for management of ocular angiogenesis: A comprehensive review
Background Angiogenic ocular diseases address the main source of vision impairment or
irreversible vision loss. The angiogenesis process depends on the balance between the pro …
irreversible vision loss. The angiogenesis process depends on the balance between the pro …
The Hitchhiker's guide to human therapeutic nanoparticle development
TI Ramos, CA Villacis-Aguirre, KV López-Aguilar… - Pharmaceutics, 2022 - mdpi.com
Nanomedicine plays an essential role in developing new therapies through novel drug
delivery systems, diagnostic and imaging systems, vaccine development, antibacterial tools …
delivery systems, diagnostic and imaging systems, vaccine development, antibacterial tools …
Melatonin loaded poly (lactic-co-glycolic acid)(PLGA) nanoparticles reduce inflammation, inhibit apoptosis and protect rat's liver from the hazardous effects of CCL4
Liver is an important organ that carries out major important functions including the
detoxification of harmful chemicals. Numerous studies have lately focused on the impact of …
detoxification of harmful chemicals. Numerous studies have lately focused on the impact of …