Peripheral nerve repair and regeneration remains among the greatest challenges in tissue
engineering and regenerative medicine. Even though peripheral nerve injuries (PNIs) are …

Pain is the major symptom of osteoarthritis (OA) and is an important factor in strategies to
manage this disease. However, the current standard of care does not provide satisfactory …

A comprehensive understanding of the cellular heterogeneity and molecular mechanisms
underlying the development, homeostasis, and disease of human intervertebral disks (IVDs) …

This review presents evidence that the skin mast cell, in particular the MCTC subtype, is the
primary effector cell in urticaria. Mast cells are located in the upper dermis, the ideal situation …

Evidence suggests that the Parkinson's disease (PD) pathogenesis is strongly associated
with bidirectional pathways in the microbiota-gut-brain axis (MGBA), and psychobiotics may …

Since its discovery, nerve growth factor (NGF) has long occupied a critical role in
developmental and adult neurobiology for its many important regulatory functions on the …

Endometriosis (EMS) is the most common gynecological disease in women of reproductive
age, and it is associated with chronic pelvic pain, dyspareunia and infertility. As a …

Diabetic keratopathy (DK) is a common, but underdiagnosed, ocular complication of
diabetes mellitus (DM) that has a significant economic burden. It is characterised by …

Cell-surface protein-protein interactions (PPIs) mediate cell-cell communication, recognition,
and responses. We executed an interactome screen of 564 human cell-surface and secreted …

Stressors ranging from psychogenic/social to neurogenic/injury to systemic/microbial can
impact microglial inflammatory processes, but less is known regarding their effects on …