[HTML][HTML] Alterations of tumor suppressor and tumor-related genes in the development and progression of gastric cancer
G Tamura - World journal of gastroenterology: WJG, 2006 - ncbi.nlm.nih.gov
The development and progression of gastric cancer involves a number of genetic and
epigenetic alterations of tumor suppressor and tumor-related genes. The majority of …
epigenetic alterations of tumor suppressor and tumor-related genes. The majority of …
Epigenetic versus genetic alterations in the inactivation of E-cadherin
G Strathdee - Seminars in cancer biology, 2002 - Elsevier
Genetic mutation of genes that inhibit the formation of tumours has long been known to be
one of the main driving forces in the development of cancer. Inactivation of one such gene, E …
one of the main driving forces in the development of cancer. Inactivation of one such gene, E …
Deregulated expression of the PER1 , PER2 and PER3 genes in breast cancers
ST Chen, KB Choo, MF Hou, KT Yeh, SJ Kuo… - …, 2005 - academic.oup.com
Disruption of circadian rhythm may be a risk factor in the development of breast cancer, but
molecular changes in circadian rhythm controlled genes in breast cancer cells are still …
molecular changes in circadian rhythm controlled genes in breast cancer cells are still …
[HTML][HTML] Promoter methylation and silencing of PTEN in gastric carcinoma
Abstract The PTEN/MMAC1/TEP1 gene (phosphatase and tensin homolog deleted on
chromosome 10/mutated in multiple advanced cancers/TGF-β regulated and epithelial cell …
chromosome 10/mutated in multiple advanced cancers/TGF-β regulated and epithelial cell …
The Epstein–Barr virus oncogene product, latent membrane protein 1, induces the downregulation of E-cadherin gene expression via activation of DNA …
CN Tsai, CL Tsai, KP Tse… - Proceedings of the …, 2002 - National Acad Sciences
The latent membrane protein (LMP1) of Epstein–Barr virus (EBV) is expressed in EBV-
associated nasopharyngeal carcinoma, which is notoriously metastatic. Although it is …
associated nasopharyngeal carcinoma, which is notoriously metastatic. Although it is …
Methylation of protocadherin 10, a novel tumor suppressor, is associated with poor prognosis in patients with gastric cancer
BACKGROUND & AIMS: By using methylation-sensitive representational difference
analysis, we identified protocadherin 10 (PCDH10), a gene that encodes a protocadherin …
analysis, we identified protocadherin 10 (PCDH10), a gene that encodes a protocadherin …
Aberrant DNA methylation in non-neoplastic gastric mucosa of H. pylori infected patients and effect of eradication
F Perri, R Cotugno, A Piepoli, A Merla… - Official journal of the …, 2007 - journals.lww.com
BACKGROUND Gene promoter methylation is an epigenetic event leading to gene
silencing. This mechanism is particularly relevant in cancer since it can interfere with the …
silencing. This mechanism is particularly relevant in cancer since it can interfere with the …
Detection of gene promoter hypermethylation in the tumor and serum of patients with gastric carcinoma
Purpose: Aberrant promoter methylation, an alternative mechanism for gene silencing, is
frequently detected in gastric cancer. We studied the feasibility of detecting aberrant …
frequently detected in gastric cancer. We studied the feasibility of detecting aberrant …
Molecular basis of gastric cancer development and progression
L Zheng, L Wang, J Ajani, K Xie - Gastric cancer, 2004 - Springer
Gastric cancer is one of the leading causes of cancer death worldwide. Because of its
heterogeneity, gastric cancer has been an interesting model for studying carcinogenesis …
heterogeneity, gastric cancer has been an interesting model for studying carcinogenesis …
DeTiN: overcoming tumor-in-normal contamination
Abstract Comparison of sequencing data from a tumor sample with data from a matched
germline control is a key step for accurate detection of somatic mutations. Detection …
germline control is a key step for accurate detection of somatic mutations. Detection …