[HTML][HTML] The pivotal role of NF-kB in the pathogenesis and therapeutics of Alzheimer's disease
Alzheimer's Disease (AD) is the most common neurodegenerative disease worldwide, with a
high prevalence that is expected to double every 20 years. Besides the formation of Aβ …
high prevalence that is expected to double every 20 years. Besides the formation of Aβ …
[HTML][HTML] The effects of microglia-associated neuroinflammation on Alzheimer's disease
C Wang, S Zong, X Cui, X Wang, S Wu… - Frontiers in …, 2023 - frontiersin.org
Alzheimer's disease (AD) is defined as a severe chronic degenerative neurological disease
in human. The pathogenic mechanism of AD has been convincingly elucidated by the …
in human. The pathogenic mechanism of AD has been convincingly elucidated by the …
[HTML][HTML] Signal pathways in the treatment of Alzheimer's disease with traditional Chinese medicine
MR Ding, YJ Qu, B Hu, HM An - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Aim of the review This study aimed to reveal the classical signal pathways and important
potential targets of traditional Chinese medicine (TCM) for treating Alzheimer's disease (AD) …
potential targets of traditional Chinese medicine (TCM) for treating Alzheimer's disease (AD) …
A potential link between visceral obesity and risk of Alzheimer's disease
Alzheimer's disease (AD) is the most common type of dementia characterized by the
deposition of amyloid beta (Aβ) plaques and tau-neurofibrillary tangles in the brain. Visceral …
deposition of amyloid beta (Aβ) plaques and tau-neurofibrillary tangles in the brain. Visceral …
Forsythoside B attenuates neuro-inflammation and neuronal apoptosis by inhibition of NF-κB and p38-MAPK signaling pathways through activating Nrf2 post spinal …
M Xia, Y Zhang, H Wu, Q Zhang, Q Liu, G Li… - International …, 2022 - Elsevier
Background Spinal cord injury (SCI) is a ruinous neurological pathology that results in
locomotor and sensory impairment. Neuro-inflammation and secondary neuronal apoptosis …
locomotor and sensory impairment. Neuro-inflammation and secondary neuronal apoptosis …
[HTML][HTML] NF-κB Pathway and Its Inhibitors: A Promising Frontier in the Management of Alzheimer's Disease
The nuclear factor kappa B (NF-κB) pathway has emerged as a pivotal player in the
pathogenesis of various diseases, including neurodegenerative illnesses like Alzheimer's …
pathogenesis of various diseases, including neurodegenerative illnesses like Alzheimer's …
[HTML][HTML] Systematic review of the common pathophysiological mechanisms in COVID-19 and neurodegeneration: the role of bioactive compounds and natural …
The novel coronavirus (2019-nCoVCOVID-19) belongs to the Beta coronavirus family, which
contains MERS-CoV (Middle East respiratory syndrome coronavirus) and SARS-CoV …
contains MERS-CoV (Middle East respiratory syndrome coronavirus) and SARS-CoV …
[HTML][HTML] Review of the therapeutic potential of Forsythiae Fructus on the central nervous system: active ingredients and mechanisms of action
L Zhang, F Lang, J Feng, J Wang - Journal of Ethnopharmacology, 2023 - Elsevier
Abstract Ethnopharmacological relevance Traditional Chinese medicine has gained
significant attention in recent years owing to its multi-component, multi-target, and multi …
significant attention in recent years owing to its multi-component, multi-target, and multi …
Aureonitol Analogues and Orsellinic Acid Esters Isolated from Chaetomium elatum and Their Antineuroinflammatory Activity
F Ju, QX Kuang, QZ Li, LJ Huang, WX Guo… - Journal of Natural …, 2021 - ACS Publications
Overexpression of various pro-inflammatory factors in microglial cells tends to induce
neurodegenerative diseases, for which there is no effective therapy available. Aureonitol (1) …
neurodegenerative diseases, for which there is no effective therapy available. Aureonitol (1) …
[HTML][HTML] Neuroprotective effect of astragalin via activating PI3K/Akt-mTOR-mediated autophagy on APP/PS1 mice
CZ Yang, SH Wang, RH Zhang, JH Lin, YH Tian… - Cell Death …, 2023 - nature.com
As a small molecule flavonoid, astragalin (AST) has anti-inflammatory, anti-cancer, and anti-
oxidation effects. However, the impact and molecular mechanism of AST in Alzheimer's …
oxidation effects. However, the impact and molecular mechanism of AST in Alzheimer's …