Very low lead exposures and children's neurodevelopment

DC Bellinger - Current opinion in pediatrics, 2008 - journals.lww.com
Very low lead exposures and children's neurodevelopment : Current Opinion in Pediatrics Very
low lead exposures and children's neurodevelopment : Current Opinion in Pediatrics Log in or …

[HTML][HTML] Animal models of childhood exposure to lead or manganese: evidence for impaired attention, impulse control, and affect regulation and assessment of …

DR Smith, BJ Strupp - Neurotherapeutics, 2023 - Elsevier
Behavioral disorders involving attention and impulse control dysfunction, such as ADHD, are
among the most prevalent disorders in children and adolescents, with significant impact on …

Low-level lead exposure impairs fronto-executive functions: A call to update the DSM–5 with lead poisoning as a neurodevelopmental disorder.

LS Neuwirth, OE Lopez, JS Schneider… - Psychology & …, 2020 - psycnet.apa.org
Abstract Lead (Pb 2+) exposure continues to occur despite efforts to reduce its
environmental sources and affects millions of children in the United States alone. Finding Pb …

Maternal choline supplementation lessens the behavioral dysfunction produced by developmental manganese exposure in a rodent model of ADHD

SL Howard, SA Beaudin, BJ Strupp… - Neurotoxicology and …, 2024 - Elsevier
Studies in children have reported associations between elevated manganese (Mn)
exposure and ADHD-related symptoms of inattention, impulsivity/hyperactivity, and …

Effects of chronic lead intoxication on rat serotoninergic system and anxiety behavior

W Sansar, MM Bouyatas, S Ahboucha, H Gamrani - Acta histochemica, 2012 - Elsevier
Chronic lead exposure has been shown to produce behavioral disturbances in human and
animal models. These disturbances are associated with alterations in monoaminergic …

[HTML][HTML] Assessing attention in rodents

PJ Bushnell, BJ Strupp - 2011 - europepmc.org
“Attention” refers to a variety of hypothetical constructs by which the nervous system
apprehends and organizes sensory input and generates coordinated behavior. Although it …

Succimer chelation improves learning, attention, and arousal regulation in lead-exposed rats but produces lasting cognitive impairment in the absence of lead …

DE Stangle, DR Smith, SA Beaudin… - Environmental …, 2007 - ehp.niehs.nih.gov
Background There is growing pressure for clinicians to prescribe chelation therapy at only
slightly elevated blood lead levels. However, very few studies have evaluated whether …

The scientific basis for chelation: animal studies and lead chelation

D Smith, BJ Strupp - Journal of Medical Toxicology, 2013 - Springer
This presentation summarizes several of the rodent and non-human studies that we have
conducted to help inform the efficacy and clinical utility of succimer (meso-2, 3 …

Methylphenidate alleviates manganese-induced impulsivity but not distractibility

SA Beaudin, BJ Strupp, W Uribe, L Ysais… - Neurotoxicology and …, 2017 - Elsevier
Recent studies from our lab have demonstrated that postnatal manganese (Mn) exposure in
a rodent model can cause lasting impairments in fine motor control and attention, and that …

Disturbed sensorimotor and electrophysiological patterns in lead intoxicated rats during development are restored by curcumin I

H Benammi, H Erazi, O El Hiba, L Vinay, H Bras… - PLoS …, 2017 - journals.plos.org
Lead poisoning is one of the most significant health problem of environmental origin. It is
known to cause different damages in the central and peripheral nervous system which could …