This article is part of a Minifocus on collective cell migration. For further reading, please see
related articles: ʻMechanisms of collective cell migration at a glanceʼ by Olga Ilina and …

Liquid biopsies have been considered the holy grail in achieving effective cancer
management, with blood tests offering a minimally invasive, safe, and sensitive alternative or …

Platelets are specialized hemostatic cells that circulate in the blood as anucleate cytoplasts.
We report that platelets unexpectedly possess a functional spliceosome, a complex that …

Dermal wounds, both acute and chronic, represent a significant clinical challenge, and
therefore the development of novel biomaterial-based skin substitutes to promote skin repair …

Background Since mature erythrocytes are terminally differentiated cells without nuclei and
organelles, it is commonly thought that they do not contain nucleic acids. In this study, we …

Blood platelet RNA-sequencing is increasingly used among the scientific community.
Aberrant platelet transcriptome is common in cancer or cardiovascular disease, but …

Wound healing is a highly coordinated and complex process involving various cell types,
chemical mediators and the surrounding extracellular matrix, resulting in a tightly …

Platelets express TLR4 receptors, but its ligand LPS does not directly activate thrombotic
functions nor, obviously, transcription by these anucleate cells. Platelets, however, store …

Platelets play a major role in the metastatic dissemination of tumor cells in vivo. Recent
evidence reveals megakaryocyte‐derived platelet pre‐mRNA is spliced to mRNA and then …

Background—In sickle cell disease, ischemia-reperfusion injury and intravascular hemolysis
produce endothelial dysfunction and vasculopathy characterized by reduced nitric oxide and …