Photons or electrons? A critical comparison of electrochemistry and photoredox catalysis for organic synthesis
NES Tay, D Lehnherr, T Rovis - Chemical reviews, 2021 - ACS Publications
Redox processes are at the heart of synthetic methods that rely on either electrochemistry or
photoredox catalysis, but how do electrochemistry and photoredox catalysis compare? Both …
photoredox catalysis, but how do electrochemistry and photoredox catalysis compare? Both …
What blocks more anticancer platinum complexes from experiment to clinic: Major problems and potential strategies from drug design perspectives
K Peng, BB Liang, W Liu, ZW Mao - Coordination Chemistry Reviews, 2021 - Elsevier
Encouraged by the worldwide success of cisplatin in the field of cancer chemotherapy,
intensive works have been conducted to explore more platinum coordination complexes as …
intensive works have been conducted to explore more platinum coordination complexes as …
Photocatalytic umpolung strategy for the synthesis of α-amino phosphine oxides and deuterated derivatives
C Ma, X Li, X Chen, X He, ST Zhang, YQ Jiang… - Organic …, 2023 - ACS Publications
Direct, economical, and green synthesis of deuterated α-amino phosphine oxides remains
an elusive challenge in synthetic chemistry. Herein, we report a visible-light-driven …
an elusive challenge in synthetic chemistry. Herein, we report a visible-light-driven …
Selected organophosphorus compounds with biological activity. Applications in medicine
S Demkowicz, J Rachon, M Daśko, W Kozak - RSC advances, 2016 - pubs.rsc.org
The purpose of this article is to provide an overview of the latest applications of
organophosphorus compounds (OPs) that exhibit biological activity. A large family of OPs …
organophosphorus compounds (OPs) that exhibit biological activity. A large family of OPs …
Recent Advances in the Construction of Phosphorus‐Substituted Heterocycles, 2009–2019
L Chen, XY Liu, YX Zou - Advanced Synthesis & Catalysis, 2020 - Wiley Online Library
Phosphorus‐substituted heterocycles represent an important class of organophosphorus
compounds, which not only widely exist in biologically active pharmaceuticals …
compounds, which not only widely exist in biologically active pharmaceuticals …
Bisphosphonates: The role of chemistry in understanding their biological actions and structure-activity relationships, and new directions for their therapeutic use
Abstract The bisphosphonates ((HO) 2 P (O) CR 1 R 2 P (O)(OH) 2, BPs) were first shown to
inhibit bone resorption in the 1960s, but it was not until 30 years later that a detailed …
inhibit bone resorption in the 1960s, but it was not until 30 years later that a detailed …
The role of the phosphorus atom in drug design
JB Rodriguez, C Gallo‐Rodriguez - ChemMedChem, 2019 - Wiley Online Library
Although the phosphorus atom is found in a variety of oxidation states, most of the
phosphorus‐containing molecules of pharmacological importance possess phosphorus in …
phosphorus‐containing molecules of pharmacological importance possess phosphorus in …
Phosphine Oxides from a Medicinal Chemist's Perspective: Physicochemical and in Vitro Parameters Relevant for Drug Discovery
P Finkbeiner, JP Hehn, C Gnamm - Journal of Medicinal …, 2020 - ACS Publications
Phosphine oxides and related phosphorus-containing functional groups such as
phosphonates and phosphinates are established structural motifs that are still …
phosphonates and phosphinates are established structural motifs that are still …
The Kabachnik–Fields reaction: Mechanism and synthetic use
G Keglevich, E Bálint - Molecules, 2012 - mdpi.com
The Kabachnik–Fields (phospha-Mannich) reaction involving the condensation of primary or
secondary amines, oxo compounds (aldehydes and ketones) and> P (O) H species …
secondary amines, oxo compounds (aldehydes and ketones) and> P (O) H species …
Enantioselective Palladium‐Catalyzed Hydrophosphinylation of Allenes with Phosphine Oxides: Access to Chiral Allylic Phosphine Oxides
Z Yang, J Wang - Angewandte Chemie, 2021 - Wiley Online Library
A Pd‐catalyzed hydrophosphinylation of alkyl and aryl‐oxyallenes with phosphine oxides
has been developed for the efficient and rapid construction of a family of chiral allylic …
has been developed for the efficient and rapid construction of a family of chiral allylic …