Angiogenesis, the formation of new blood vessels, is a complex and dynamic process
regulated by various pro-and anti-angiogenic molecules, which plays a crucial role in tumor …

Cancer microenvironment is critical for tumorigenesis and cancer progression. The
extracellular matrix (ECM) interacts with tumor and stromal cells to promote cancer cells …

Many efforts have been made to achieve targeted delivery of anticancer drugs to enhance
their efficacy and to reduce their adverse effects. These efforts include the development of …

Characterized by the expression of the critical transcription factor forkhead box protein P3,
regulatory T (Treg) cells are an essential part of the immune system, with a dual effect on the …

As a result of metabolic reprogramming, cancer cells display high rates of glycolysis,
causing an excess production of lactate along with an increase in extracellular acidity …

NIR-II imaging is developed rapidly for noninvasive deep tissue inspection with high spatio-
temporal resolution, taking advantage of diminished autofluorescence and light attenuation …

Even though radiotherapy is the most important therapeutic strategy for colon cancer
treatment, there is an enormous demand to improve radiosensitivity in solid tumor …

Pancreatic cancer is one of the common malignant tumors of the digestive system and is
known as the “king of cancers”. It is extremely difficult to diagnose at an early stage, the …

With the development of nanomedicine technology, stimuli-responsive nanocarriers play an
increasingly important role in antitumor therapy. Compared with the normal physiological …

The prognosis with pancreatic cancer is among the poorest of any human cancer. One of the
important factors is the tumor hypoxia. Targeting tumor hypoxia is considered a desirable …