Clinical practice guidelines for therapeutic drug monitoring of vancomycin in the framework of model-informed precision dosing: a consensus review by the Japanese …
K Matsumoto, K Oda, K Shoji, Y Hanai, Y Takahashi… - Pharmaceutics, 2022 - mdpi.com
Background: To promote model-informed precision dosing (MIPD) for vancomycin (VCM),
we developed statements for therapeutic drug monitoring (TDM). Methods: Ten clinical …
we developed statements for therapeutic drug monitoring (TDM). Methods: Ten clinical …
Therapeutic monitoring of vancomycin for serious methicillin-resistant Staphylococcus aureus infections: A revised consensus guideline and review by the American …
Methods These are the consensus statements and guideline of ASHP, IDSA, the Pediatric
Infectious Diseases Society (PIDS), and SIDP. Guideline panel composition consisted of …
Infectious Diseases Society (PIDS), and SIDP. Guideline panel composition consisted of …
An update on population pharmacokinetic analyses of vancomycin, part I: in adults
A Aljutayli, A Marsot, F Nekka - Clinical pharmacokinetics, 2020 - Springer
Despite the wide clinical use of vancomycin, controversy remains regarding its optimal
dosage regimens. This can be attributed to the large between-and within-subject variability …
dosage regimens. This can be attributed to the large between-and within-subject variability …
A model averaging/selection approach improves the predictive performance of model‐informed precision dosing: vancomycin as a case study
DW Uster, SL Stocker, JE Carland… - Clinical …, 2021 - Wiley Online Library
Many important drugs exhibit substantial variability in pharmacokinetics and
pharmacodynamics leading to a loss of the desired clinical outcomes or significant adverse …
pharmacodynamics leading to a loss of the desired clinical outcomes or significant adverse …
Optimal practice for vancomycin therapeutic drug monitoring: position statement from the anti-infectives committee of the international association of therapeutic drug …
SE Reuter, SL Stocker, JWC Alffenaar… - Therapeutic Drug …, 2022 - journals.lww.com
Individualization of vancomycin dosing based on therapeutic drug monitoring (TDM) data is
known to improve patient outcomes compared with fixed or empirical dosing strategies …
known to improve patient outcomes compared with fixed or empirical dosing strategies …
Prediction of vancomycin dose on high-dimensional data using machine learning techniques
X Huang, Z Yu, X Wei, J Shi, Y Wang… - Expert Review of …, 2021 - Taylor & Francis
Objectives Despite therapeutic vancomycin is regularly monitored, its dose requirements
vary considerably between individuals. Various innovative vancomycin dosing strategies …
vary considerably between individuals. Various innovative vancomycin dosing strategies …
Continuous learning in model‐informed precision dosing: a case study in pediatric dosing of vancomycin
Model‐informed precision dosing (MIPD) leverages pharmacokinetic (PK) models to tailor
dosing to an individual patient's needs, improving attainment of therapeutic drug exposure …
dosing to an individual patient's needs, improving attainment of therapeutic drug exposure …
[HTML][HTML] Towards precision dosing of vancomycin in critically ill patients: an evaluation of the predictive performance of pharmacometric models in ICU patients
CB Cunio, DW Uster, JE Carland, H Buscher… - Clinical Microbiology …, 2021 - Elsevier
Objectives Vancomycin dose recommendations depend on population pharmacokinetic
models. These models have not been adequately assessed in critically ill patients, who …
models. These models have not been adequately assessed in critically ill patients, who …
Vancomycin dosing and therapeutic drug monitoring practices: guidelines versus real-life
T Van Der Heggen, FM Buyle, B Claus… - International Journal of …, 2021 - Springer
Background Correct dosing and therapeutic drug monitoring (TDM) practices are essential
when aiming for optimal vancomycin treatment. Objective To assess target attainment after …
when aiming for optimal vancomycin treatment. Objective To assess target attainment after …
Pharmacokinetics of antibiotics in pediatric intensive care: fostering variability to attain precision medicine
M Gijsen, D Vlasselaers, I Spriet, K Allegaert - Antibiotics, 2021 - mdpi.com
Children show important developmental and maturational changes, which may contribute
greatly to pharmacokinetic (PK) variability observed in pediatric patients. These PK …
greatly to pharmacokinetic (PK) variability observed in pediatric patients. These PK …