Optogenetic is a technique that combines optics and genetics to control specific neurons.
This technique usually uses adenoviruses that encode photosensitive protein. The …

Excitatory projection neurons and inhibitory interneurons primarily accomplish the neural
activity of the cerebral cortex, and an imbalance of excitatory-inhibitory neural networks may …

Epilepsy, a fairly common neurological disorder, is linked to various sequelae and greatly
impairs the quality of life. Meanwhile, there is evidence to suggest an association between …

Epilepsy affects 1% of the general population and 30% of patients are resistant to
antiepileptic drugs. Although optogenetics is an efficient antiepileptic strategy, the difficulty of …

Lennox-Gastaut syndrome is a severe drug-resistant developmental and epileptic
encephalopathy with slow spike and wave on EEG (DEE-SSW) composing about 1–2% of …

The field of drug delivery has significantly advanced tumor therapy, yet challenges such as
the predictability of treatment outcomes and the real‐time monitoring of tumor progression …

Epilepsies are a complex and heterogeneous group of disorders mainly characterized by
the presence of recurrent, spontaneous, and unpredictable seizures. Epilepsy affects 1–2 …

About one percent of the world's population is affected by epilepsy. Epilepsy-induced
psychiatric co-morbidity and mortality impose a huge burden on patients, their families, and …

Introduction Developmental and epileptic encephalopathies (DEE) is a group of epilepsies
where the epileptic activity, seizures and the underlying neurobiology contributes to …

Human programmed cell death 4 (PDCD4) has been reported to participate in multiple
neurological diseases. However, the role of PDCD4 in epilepsy, as well as its underlying …