Due to their biocompatibility, non-toxicity, and surface-conjugation capabilities, liposomes
are effective nanocarriers that can encapsulate chemotherapeutic drugs and facilitate …

Introduction A major challenge in treating central nervous system (CNS) disorders is to
achieve adequate drug delivery across the blood–brain barrier (BBB). Receptor-mediated …

Abstract Alzheimer's disease (AD), one of the most common chronic neurodegenerative
diseases, is characterized by memory impairment, synaptic dysfunction, and character …

Invasive fungal infections, including meningitis, cause a high mortality rate due to few
available antifungal drugs and frequently associated side effects and quick emergence of …

The prevalence of central nervous system (CNS) diseases is on the rise as the population
ages. The presence of various obstacles, particularly the blood-brain barrier (BBB), poses a …

Extracellular vesicles (EVs), involved in essential physiological and pathological processes
of the organism, have emerged as powerful tools for disease treatment owing to their unique …

Intranasal drug delivery is as a noninvasive and efficient approach extensively utilized for
treating the local, central nervous system, and systemic diseases. Despite numerous …

Despite significant advancements in CNS research, CNS illnesses are the most important
and serious cause of mental disability worldwide. These facts show a tremendous unmet …

Progress in treatment for glioblastoma is hindered by the blood-brain barrier (BBB). In
genetic mouse models recapitulating brain invasion and abnormal angiogenesis of human …

Despite the clear benefits demonstrated by immunotherapy, there is still an inevitable off-
target effect resulting in serious adverse immune reactions. In recent years, the research and …