Since the discovery of place cells, hippocampus-dependent spatial navigation has proven to
be an ideal model system for resolving the relationship between neural coding and …

Background: Population voltage imaging is used for studying brain physiology and brain
circuits. Using a genetically encoded voltage indicator (GEVI),“VSFP” or “ASAP2s”, or a …

Detection of somatosensory inputs requires conversion of external stimuli into electrical
signals by activation of primary sensory neurons. The mechanisms by which heterogeneous …

Optical biosensing has proven its efficacy in diverse clinical applications, including
intraoperative guidance, vital sign monitoring, disease diagnosis, and treatment monitoring …

Our ability to learn relies on the potential of neuronal circuits to change through experience.
Recent advances in genetic tools and in vivo imaging have enabled novel investigations …

Genetically-encoded indicators of neuronal activity enable the labeling of a genetically
defined population of neurons to optically monitor their activities. However, researchers …

Neural synchronization at gamma (∼ 40 Hz) frequencies is believed to contribute to brain
function and be deficient in disorders including Alzheimer's disease and schizophrenia …

Focal seizure propagation is classically thought to be spatially contiguous. However,
propagation through the epileptic network–a collection of disparate epileptic nodes-has …

The prefrontal cortex (PFC) is required for many cognitive processes that are disrupted in
conditions such as schizophrenia. The PFC is composed of neuronal networks which are …

Emotional responses arise from limbic circuits including the hippocampus and amygdala. In
the human brain, beta-frequency communication between these structures correlates with …