Kidney involvement in patients with systemic lupus erythematosus—lupus nephritis (LN)—is
one of the most important and common clinical manifestations of this disease and occurs in …

Dendritic cells (DCs) are chief inducers of adaptive immunity and regulate local
inflammatory responses across the body. Together with macrophages, the other main type of …

Background Systemic lupus erythematosus (SLE) is a multisystemic, chronic inflammatory
disease characterized by destructive systemic organ involvement, which could cause the …

Epithelial-mesenchymal transition (EMT) is defined as a process in which differentiated
epithelial cells undergo phenotypic transformation into myofibroblasts capable of producing …

The immune pathways that define treatment response and non-response in lupus nephritis
(LN) are unknown. To characterize these intra-kidney pathways, transcriptomic analysis was …

Commensal bacteria and the immune system have a close and strong relationship that
maintains a balance to control inflammation. Alterations of the microbiota, known as …

Introduction Leaky gut has been linked to autoimmune disorders including lupus. We
previously reported upregulation of anti-flagellin antibodies in the blood of lupus patients …

Systemic lupus erythematosus (SLE) is a serious autoimmune disease with variety of organ
manifestations. The most dreadful one, affecting the majority of SLE patients, is kidney …

Non‐classical monocytes infiltrate the kidney parenchyma and participate in tissue damage
in patients with lupus nephritis (LN). Circulating microparticles (MPs) seem to play critical …

Fractalkine (FKN), also known as chemokine (C-X3-C motif) ligand 1, constitutes an
intriguing chemokine with a documented role in the development of numerous inflammatory …