Multifunctional curcumin mediate multitherapeutic effects

A Shehzad, M Qureshi, MN Anwar… - Journal of food …, 2017 - Wiley Online Library
Inflammation can promote the development of arthritis, obesity, cardiovascular, type II
diabetes, pancreatitis, metabolic and neurodegenerative diseases, and certain types of …

[HTML][HTML] Antioxidants in cervical cancer: chemopreventive and chemotherapeutic effects of polyphenols

F Di Domenico, C Foppoli, R Coccia… - Biochimica et Biophysica …, 2012 - Elsevier
Cervical cancer lesions are a major threat to the health of women, representing the second
most common cancer worldwide. The unanimously recognized etiological factor in the …

[HTML][HTML] Unleashing ferroptosis in human cancers: targeting ferroptosis suppressor protein 1 for overcoming therapy resistance

J Lee, JL Roh - Antioxidants, 2023 - mdpi.com
Ferroptosis, a recently identified form of regulated cell death characterized by the iron-
dependent accumulation of lethal lipid peroxidation, has gained increasing attention in …

The combination of curcumin and 5-fluorouracil in cancer therapy

Y Wei, P Yang, S Cao, L Zhao - Archives of pharmacal research, 2018 - Springer
Fluorouracil (5-FU) alone or in combination with other therapeutic drugs has been widely
used for clinical treatment of various cancers. However, 5-FU-based chemotherapy has …

Curcumin shows excellent therapeutic effect on psoriasis in mouse model

D Kang, B Li, L Luo, W Jiang, Q Lu, M Rong, R Lai - Biochimie, 2016 - Elsevier
Curcumin is an active herbal ingredient possessing surprisingly wide range of beneficial
properties, including anti-inflammatory, antioxidant, chemopreventive and chemotherapeutic …

[HTML][HTML] Curcumin potentiates antitumor activity of cisplatin in bladder cancer cell lines via ROS-mediated activation of ERK1/2

BH Park, JE Lim, HG Jeon, SI Seo, HM Lee, HY Choi… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Resistance of bladder cancer to cisplatin is a major obstacle to successful treatment. In the
current study, we investigated the apoptotic effects of curcumin and cisplatin co-treatment in …

[HTML][HTML] Intracellular Ca2 + Imbalance Critically Contributes to Paraptosis

E Kim, DM Lee, MJ Seo, HJ Lee… - Frontiers in cell and …, 2021 - frontiersin.org
Paraptosis is a type of programmed cell death that is characterized by dilation of the
endoplasmic reticulum (ER) and/or mitochondria. Since paraptosis is morphologically and …

Phytochemicals: A potential next generation agent for radioprotection

BP Jit, S Pattnaik, R Arya, R Dash, SS Sahoo… - Phytomedicine, 2022 - Elsevier
Background Radiation hazards are accountable for extensive damage in the biological
system and acts as a public health burden. Owing to the rapid increasing in radiation …

Curcumin and lung cancer—a review

HJ Mehta, V Patel, RT Sadikot - Targeted oncology, 2014 - Springer
Curcumin (diferuloylmethane) is the most important component of the spice turmeric and is
derived from the rhizome of the East Indian plant Curcuma longa. Curcumin has been used …

[HTML][HTML] Molecular targets for anticancer redox chemotherapy and cisplatin-induced ototoxicity: the role of curcumin on pSTAT3 and Nrf-2 signalling

AR Fetoni, F Paciello, D Mezzogori, R Rolesi… - British journal of …, 2015 - nature.com
Background: In oncology, an emerging paradigm emphasises molecularly targeted
approaches for cancer prevention and therapy and the use of adjuvant chemotherapeutics …