Phytochemicals: A potential next generation agent for radioprotection

BP Jit, S Pattnaik, R Arya, R Dash, SS Sahoo… - Phytomedicine, 2022 - Elsevier
Background Radiation hazards are accountable for extensive damage in the biological
system and acts as a public health burden. Owing to the rapid increasing in radiation …

Molecular mechanisms underlying curcumin‐mediated therapeutic effects in type 2 diabetes and cancer

M Wojcik, M Krawczyk, P Wojcik… - Oxidative medicine …, 2018 - Wiley Online Library
The growing prevalence of age‐related diseases, especially type 2 diabetes mellitus
(T2DM) and cancer, has become global health and economic problems. Due to multifactorial …

The relationship between nutrition and prostate cancer: is more always better?

EM Masko, EH Allott, SJ Freedland - European urology, 2013 - Elsevier
CONTEXT: Prostate cancer (PCa) remains one of the most diagnosed malignancies in the
world, correlating with regions where men consume more of a so-called Western-style diet …

Andrographis-mediated chemosensitization through activation of ferroptosis and suppression of β-catenin/Wnt-signaling pathways in colorectal cancer

P Sharma, T Shimura, JK Banwait, A Goel - Carcinogenesis, 2020 - academic.oup.com
Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality in
the USA. As much as 50–60% of CRC patients develop resistance to 5-fluorouracil (5FU) …

Polyphenol compounds and PKC signaling

J Das, R Ramani, MO Suraju - … et Biophysica Acta (BBA)-General Subjects, 2016 - Elsevier
Background Naturally occurring polyphenols found in food sources provide huge health
benefits. Several polyphenolic compounds are implicated in the prevention of disease …

Curcumin attenuates oxaliplatin-induced liver injury and oxidative stress by activating the Nrf2 pathway

Y Lu, S Wu, B Xiang, L Li, Y Lin - Drug design, development and …, 2020 - Taylor & Francis
Purpose Oxaliplatin (OXA)-induced liver injury is one of the main limiting factors affecting the
efficacy of OXA-based chemotherapy in patients with colorectal liver metastases. In addition …

Enhanced oral bioavailability and anticancer activity of novel curcumin loaded mixed micelles in human lung cancer cells

S Patil, B Choudhary, A Rathore, K Roy, K Mahadik - Phytomedicine, 2015 - Elsevier
Background Curcumin has a wide range of pharmacological activities including antioxidant,
anti-inflammatory, antidiabetic, antibacterial, wound healing, antiatherosclerotic …

Nutrition and healthy ageing: calorie restriction or polyphenol‐rich “MediterrAsian” diet?

K Pallauf, K Giller, P Huebbe… - Oxidative medicine and …, 2013 - Wiley Online Library
Diet plays an important role in mammalian health and the prevention of chronic diseases
such as cardiovascular disease (CVD). Incidence of CVD is low in many parts of Asia (eg …

Combinations of the antioxidants sulforaphane or curcumin and the conventional antineoplastics cisplatin or doxorubicin as prospects for anticancer chemotherapy

M Negrette-Guzman - European journal of pharmacology, 2019 - Elsevier
Drugs used in clinical oncology have narrow therapeutic indices with adverse toxicity often
involving oxidative damage. Chemoresistance to these conventional antineoplastics is …

Curcumin reverses cis-platin resistance and promotes human lung adenocarcinoma A549/DDP cell apoptosis through HIF-1α and caspase-3 mechanisms

MX Ye, YL Zhao, Y Li, Q Miao, ZK Li, XL Ren, LQ Song… - Phytomedicine, 2012 - Elsevier
Curcumin, a yellow pigment derived from Curcuma longa Linn, has been favored by the
Eastern as dietary ingredients for centuries. During the past decade, extensive …