[HTML][HTML] The vitamin D receptor as a potential target for the treatment of age-related neurodegenerative diseases such as Alzheimer's and Parkinson's diseases: a …

W Lasoń, D Jantas, M Leśkiewicz, M Regulska… - Cells, 2023 - mdpi.com
The vitamin D receptor (VDR) belongs to the nuclear receptor superfamily of transcription
factors. The VDR is expressed in diverse brain regions and has been implicated in the …

[HTML][HTML] Sex and brain: the role of sex chromosomes and hormones in brain development and parkinson's disease

F Terrin, A Tesoriere, N Plotegher, L Dalla Valle - Cells, 2023 - mdpi.com
Sex hormones and genes on the sex chromosomes are not only key factors in the regulation
of sexual differentiation and reproduction but they are also deeply involved in brain …

Remyelination in the Central Nervous System

RJM Franklin, B Bodini… - Cold Spring Harbor …, 2024 - cshperspectives.cshlp.org
The inability of the mammalian central nervous system (CNS) to undergo spontaneous
regeneration has long been regarded as a central tenet of neurobiology. However, while this …

[HTML][HTML] Deleterious functional consequences of perfluoroalkyl substances accumulation into the myelin sheath

L Butruille, P Jubin, E Martin, MS Aigrot… - Environment …, 2023 - Elsevier
Exposure to persistent organic pollutants during the perinatal period is of particular concern
because of the potential increased risk of neurological disorders in adulthood. Here we …

[HTML][HTML] Zebrafish as an emerging model to study estrogen receptors in neural development

MJ Boueid, O El-Hage, M Schumacher… - Frontiers in …, 2023 - frontiersin.org
Estrogens induce several regulatory signals in the nervous system that are mainly mediated
through estrogen receptors (ERs). ERs are largely expressed in the nervous system, yet the …

[HTML][HTML] LXR agonism for CNS diseases: promises and challenges

R Zhang, E Wuerch, VW Yong, M Xue - Journal of Neuroinflammation, 2024 - Springer
The unfavorable prognosis of many neurological conditions could be attributed to limited
tissue regeneration in central nervous system (CNS) and overwhelming inflammation, while …

[HTML][HTML] Sexual dimorphism of early transcriptional reprogramming in degenerating peripheral nerves

AV Chernov, VI Shubayev - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
Sexual dimorphism is a powerful yet understudied factor that influences the timing and
efficiency of gene regulation in axonal injury and repair processes in the peripheral nervous …