Hepatitis C virus (HCV) is a hepatotropic RNA virus that causes progressive liver damage,
which might result in liver cirrhosis and hepatocellular carcinoma. Globally, between 64 and …

Hepatitis C virus (HCV) infects an estimated 170 million persons worldwide and thus
represents a viral pandemic, one that is five times as widespread as infection with the …

A protective vaccine against hepatitis C virus (HCV) remains an unmet clinical need. HCV
infects millions of people worldwide and is a leading cause of liver cirrhosis and …

More than 500 million people worldwide are persistently infected with the hepatitis B virus
(HBV) and/or hepatitis C virus (HCV) and are at risk of developing chronic liver disease …

A large number of studies have reported on spontaneous viral clearance rates in acute
hepatitis C infection, however most have been small, and reported rates have varied quite …

The virological and immunological features of hepatitis C virus (HCV) infection were studied
weekly for 6 months after accidental needlestick exposure in five health care workers, four of …

Although hepatitis C virus (HCV) infection is very common, identification of patients during
acute infection is rare. Consequently, little is known about the immune response during this …

CD4+ and CD8+ T cell functions are rapidly aborted during chronic infection, preventing
viral clearance. CD4+ T cell help is required throughout chronic infection so as to sustain …

Spontaneous resolution of hepatitis C virus (HCV) infection in humans usually affords long-
term immunity to persistent viremia and associated liver diseases. Here, we report that …

Since the identification of the hepatitis C virus (HCV) 20 years ago, much progress has been
made in our understanding of its life cycle and interaction with the host immune system …