The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …

The term “neuroinflammation” defines the typical inflammatory response of the brain closely
related to the onset of many neurodegenerative diseases (NDs). Neuroinflammation is well …

Alzheimer's disease (AD) is characterized by amyloid plaques and neurofibrillary tangles, in
addition to neuroinflammation and changes in brain lipid metabolism. 25 …

Studies over the last 100 years have suggested a link between inflammation, infectious
disease, and Alzheimer's Disease (AD). Understanding how the immune system changes …

Amyotrophic lateral sclerosis (ALS) is an adult-onset progressive neurodegenerative
disorder characterized by the loss of upper and lower motor neurons in the brain and spinal …

Age-related myelin damage induces inflammatory responses, yet its involvement in
Alzheimer's disease remains uncertain, despite age being a major risk factor. Using a …

Macrophages are vital tissue components involved in organogenesis, maintaining
homeostasis, and responses to disease. Mouse models have significantly improved our …

The peripheral immune system in Alzheimer's disease (AD) has not been thoroughly studied
with modern sequencing methods. To investigate epigenetic and transcriptional alterations …

Importance Older adults with lower intake and tissue levels of long-chain ω-3
polyunsaturated fatty acids (PUFAs) eicosapentaenoic acid (EPA; 20: 5) and …

The identification of diagnostic and therapeutic biomarkers for Alzheimer's Disease (AD)
remains a crucial area of research. In this study, utilizing the Weighted Gene Co-expression …