[HTML][HTML] Crosstalk between Mu-Opioid receptors and neuroinflammation: Consequences for drug addiction and pain

J Cuitavi, JV Torres-Pérez, JD Lorente… - Neuroscience & …, 2023 - Elsevier
Abstract Mu-Opioid Receptors (MORs) are well-known for participating in analgesia,
sedation, drug addiction, and other physiological functions. Although MORs have been …

Future perspectives of emerging novel drug targets and immunotherapies to control drug addiction

JA Malik, JN Agrewala - International Immunopharmacology, 2023 - Elsevier
Abstract Substance Use Disorder (SUD) is one of the major mental illnesses that is
terrifically intensifying worldwide. It is becoming overwhelming due to limited options for …

Molecular and epigenetic aspects of opioid receptors in drug addiction and pain management in sport

F Mazzeo, R Meccariello, E Guatteo - International Journal of Molecular …, 2023 - mdpi.com
Opioids are substances derived from opium (natural opioids). In its raw state, opium is a
gummy latex extracted from Papaver somniferum. The use of opioids and their negative …

Treatment with the flavonoid 7, 8-Dihydroxyflavone: A promising strategy for a constellation of body and brain disorders

M Emili, S Guidi, B Uguagliati, A Giacomini… - Critical Reviews in …, 2022 - Taylor & Francis
Flavonoids have long been known to exert benefits in various health problems. Among
them, the BDNF mimetic 7, 8-Dihydroxyflavone (7, 8-DHF) is emerging as a potential …

[HTML][HTML] Application of omics-based biomarkers in substance use disorders

L Yang, L Zhang, H Zhang, J Liu - Meta-Radiology, 2023 - Elsevier
Substance use disorder (SUD) is a type of addictive encephalopathy resulting from drug
abuse, which leads to abnormal cerebral alterations indicating neurotoxicity that is …

Addiction and human male fertility: a systematic review and a critical appraisal

M Alghobary, T Mostafa - Andrology, 2022 - Wiley Online Library
Background Addiction is a global problem that has many negative consequences on human
health as well as the quality of life. Objectives This review aimed to assess the effect of …

Substance abuse and male sexual dysfunction: what lies beneath?

T Mostafa, M Alghobary - Sexual medicine reviews, 2023 - academic.oup.com
Introduction Substance abuse has become a worldwide health problem, leading to
numerous consequences such as social problems among family members, abnormal …

Neurobiological mechanisms and related clinical treatment of addiction: a review

Y Fang, Y Sun, Y Liu, T Liu, W Hao, Y Liao - Psychoradiology, 2022 - academic.oup.com
Drug addiction or substance use disorder (SUD), has been conceptualized as a three-stage
(ie binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation/craving) …

Comparison of vitamin B12, vitamin D and folic acid blood levels in patients with schizophrenia, drug addiction and controls

AB Yazici, OA Ciner, E Yazici, AS Cilli, B Dogan… - Journal of Clinical …, 2019 - Elsevier
Schizophrenia (SCH) and drug addiction are chronic disorders that are frequently
accompanied by physical diseases, poor nutrition and reduced self-care, all of which are …

Cannabidiol prevents amphetamine relapse and modulates D1-and D2-receptor levels in mesocorticolimbic brain areas of rats

VG Metz, JLO da Rosa, DR Rossato… - European …, 2021 - Elsevier
Amphetamine (AMPH) is an addictive psychostimulant highly used worldwide and its
consumption is related to neurotoxic effects. Currently, there is no pharmacotherapy …